QUESTIONS P. aeruginosa infections are assumed to play a major role in the frequency of exacerbations and severity of chronic obstructive pulmonary disease (COPD). Colonisation with P. aeruginosa accelerates lung function decline, most probably due to more frequent exacerbations. In this retrospective study we aimed to determine the prevalence of colonisation with P. aeruginosa in COPD patients...

conclusions according to the findings of our study, there were diverse and high-level resistant p. aeruginosa strains in the major burn center in khuzestan. therefore, we faced troubles controlling the diverse p. aeruginosa clones in the burn patients. methods in a cross sectional study, a total of 75 strains of p. aeruginosa were isolated from burn patients at taleghani hospital, which is the ...

conclusions high-level antibiotic resistance can occur as a result of multidrug efflux pumps combined with other mechanisms of resistance. however, the association between over-expression of these genes and highly resistant clinical isolates cannot be ignored. results our results confirmed 203 and 60 p. aeruginosa isolates from burn and non-burn specimens, respectively. the most antibiotic resi...

Both Pseudomonas aeruginosa and the phytopathogen P. syringae produce the exopolysaccharide alginate. However, the environmental signals that trigger alginate gene expression in P. syringae are different from those in P. aeruginosa with copper being a major signal in P. syringae. In P. aeruginosa, the alternate sigma factor encoded by algT (sigma22) and the response regulator AlgR1 are required...

INTRODUCTION Segregation of patients with cystic fibrosis (CF) was implemented to prevent chronic infection with epidemic Pseudomonas aeruginosa strains with presumed detrimental clinical effects, but its effectiveness has not been carefully evaluated. METHODS The effect of strict segregation on the incidence of P. aeruginosa infection in CF patients was investigated through longitudinal prot...

The aerobic gram negative bacterium Pseudomonas aeruginosa is an opportunistic pathogen responsible for life threatening acute and chronic infections in humans. As part of chronic infection P. aeruginosa forms biofilms, which shield the encased bacteria from host immune clearance and provide an impermeable and protective barrier against currently available antimicrobial agents. P. aeruginosa ha...

Pseudomonas aeruginosa (P. aeruginosa) infections occur mostly in children immunocompromised by chronic glucocorticoids, immunosuppressive agents, or immune deficiency. When P. aeruginosa disease occurs in previously healthy children, it progresses rapidly, and most patients die of septic multiorgan failure. This case describes a 9-month-old previously healthy girl who presented with cough, fev...

The present study was undertaken in order to understand more about the interaction occurring between S. maltophilia and P. aeruginosa, which are frequently co-isolated from CF airways. For this purpose, S. maltophilia RR7 and P. aeruginosa RR8 strains, co-isolated from the lung of a chronically infected CF patient during a pulmonary exacerbation episode, were evaluated for reciprocal effect dur...

Pseudomonas aeruginosa PAO1 produces three polysaccharides, alginate, Psl, and Pel that play distinct roles in attachment and biofilm formation for monospecies biofilms. Considerably less is known about their role in the development of mixed species biofilm communities. This study has investigated the roles of alginate, Psl, and Pel during biofilm formation of P. aeruginosa in a defined and exp...