This study was performed with a laboratory-scale fixed-bed bioreactor degrading a mixture of aromatic compounds (Solvesso100). The starter culture for the bioreactor was prepared in a fermentor with a wastewater sample of a care painting facility as the inoculum and Solvesso100 as the sole carbon source. The bacterial community dynamics in the fermentor and the bioreactor were examined by a con...

Mathematical models are important tools for optimizing the design and operation of solid-state fermentation (SSF) bioreactors. Such models must describe the transport phenomena within the substrate bed and mass and energy exchanges between the bed and the other subsystems of the bioreactor, such as the bioreactor wall and headspace gases. The sophistication with which this has been done for SSF...

A lot of metallurgical processes take places in shaft furnaces, where reacting gas carrying powders flows up in packed bed of descending metallurgical materials. Gas + powder two phase flow in fixed packed bed has been investigated by author for many years 1 . At present author undertakes the investigations with moving bed. Physical model with glass bed and glass powders was constructed. The ex...

A mathematical model was developed and tested to simulate the generation and transfer of heat in solid substrate fermentation (SSF). The experimental studies were realized in a 1-L static bioreactor packed with cassava wet meal and inoculated with Aspergillus niger. A simplified pseudohomogeneous monodimensional dynamic model was used for the energy balance. Kinetic equations taking into accoun...

We report here the enhanced hemicellulase production by a Talaromyces thermophilus strain in a fed-batch fermentation using 3.6-litre laboratory-controlled bioreactor. When grown on wheat bran, this fungus produces a wide spectrum of polysaccharide-hydrolysing enzymes, mainly endo-b-1,4-xylanase (27 U/mL), b-xylosidase (1.4 U/mL), a-L-arabinofuranosidase (1.05 U/mL) and b-D-mannosidase (0.78 U/...

Serotypical application of herpes simplex virus (HSV) vectors to gene therapy (type 1) and prophylactic vaccines (types 1 and 2) has garnered substantial clinical interest recently. HSV vectors and amplicons have also been employed as helper virus constructs for manufacture of the dependovirus adeno-associated virus (AAV). Large quantities of infectious HSV stocks are requisite for these therap...

The treatment of perchlorate-contaminated groundwater was examined using two side-by-side pilot-scale fixed-bed bioreactors packed with sand or plastic media, and bioaugmented with the perchlorate-degrading bacterium Dechlorosoma sp. KJ. Groundwater containing perchlorate (77microg/L), nitrate (4mg-NO(3)/L), and dissolved oxygen (7.5mg/L) was amended with a carbon source (acetic acid) and nutri...