OBJECTIVE To determine whether perioperative transfusion of as little as one unit of packed red blood cells in the operating room or the day after surgery is associated with measurably increased odds for perioperative ischemic stroke and myocardial infarction. DESIGN Retrospective cohort study of hospital administrative data. SETTING 346 hospitals in the United States participating in the c...

A distinction must be drawn between megaloblastic and macrocytic anaemias. Not all macrocytic anaemias are megaloblastic and not all megaloblastic anaemias are macrocytic. The term macrocytosis refers to the size of red blood cells in the peripheral blood. The mean cell volume of packed red blood cells (haematocrit) may be greater than normal, or the diameters of a proportion of red blood cells...

Sickle cell disease (SCD) is an inherited blood disorder that affects red cells. The study was conducted in Elobied town during the period May 2011 to September 2011. aim of this detect abnormalities leucocytes among sickle anemic patients. 40 patients; age range between 8 months 23 years. Blood sample taken for all patients and laboratory investigation were performed using automated estimation...

objective: because of the host immunological system response against the minor blood groups of donor, transfusion in some cases, especially for patients require repeated transfusions (such as people with thalassemia), can be considered as a significant problem.  a proposed way is coating the surface antigens on red blood cells (rbcs) by covalent binding of methoxy polyethylene glycol (mpeg). th...

A marker for diagnosis of Parkinson's disease (PD), which reflects on the occurrence of peripheral pathogenic mechanisms, would potentially improve therapy. The significance of α-Synuclein (α-Syn) expression in red blood cells (RBC) is currently unclear. Here we investigated whether RBC's-expressed α-Syn may associate with PD. To this aim, we determined the levels of total and proteinase K-resi...

Red cell volumes in media sufficiently hypotonic to produce partial hemolysis have been measured with a high speed hematocrit and by an improved diffraction method. A comparison of the results shows that the upward departures from the linear relation based on the van't Hoff-Mariotte law are not observed when the volumes are measured diffractometrically. Downward departures are observed at low t...

The immunogenicity of a number of avirulent rough Salmonella dublin mutants was compared in mice and guinea-pigs. Live vaccine prepared from Strain HB 1/17 at doses of 5 X 10(7) per mouse usually gave an immunity of between 70 and 80% but in certain experiments the results were more variable and always poorer. This strain gave a cross protection of 28,5% to S. typhimurium in mice. In guinea-pig...

Because of its relative ease of operation the haemagglutination inhibition (HAI) test has been widely used in diagnostic virus serology for detecting specific antibody to haemagglutinating viruses. Erythrocyte species of animal origin are used more frequently than human group 'O' cells in haemagglutination (HA) and HAI tests because they are usually more sensitive to agglutination by certain vi...

Although pathogen reduction technology was implemented for platelet concentrates and plasma, the risk of transmission has not been completely eliminated as no inactivation procedures were red blood cells whole blood. Research therefore focused on developing methods effective in cell components. Attempts made to apply either chemical compounds (porphyrins Sylsense compounds) or photosensitizers ...

Image 1. Upper panels: Peripheral blood smears of case 1 (A) and 2 (B), showing marked anisopoikilocytosis, with formation of hemi-ghost blister cells (*) and presence of circulating erythroid precursors (insets). Lower panels: Respective values for hemoglobin (Hb), reticulocytes, platelets (PLTs), total white blood cell (WBC) count, bilirubin, lactate dehydrogenase (LDH), and creatinine levels...