BACKGROUND Hand eczema is not uncommon in children but it is rarely studied using skin-prick tests. Few reports have addressed their usefulness in children and none has specifically analyzed their use in children with hand eczema. MATERIAL AND METHODS We performed a retrospective study of all children up to 16years of age with hand eczema who were assessed in the Department of Dermatology at ...

BACKGROUND/OBJECTIVES Environmental exposure and personal susceptibility both contribute to the development of hand eczema. In this study, we investigated the effect of loss-of-function mutations in the filaggrin gene (FLG), atopic dermatitis and wet work exposure on the development of hand eczema in apprentice nurses. METHODS Dutch apprentice nurses were genotyped for the four most common FL...

Chronic hand eczema places a heavy burden on patients, often affecting their ability to work. This paper compares the cost-of-illness and treatment approaches for patients with refractory chronic hand eczema, in relation to whether the disease was occupational or unrelated to work factors. Data from 2 surveys, comprising 310 patients with chronic hand eczema insured by German statutory health i...

eczema  is  a  common  childhood  atopic  condition and treatment is with emollients,  topical corticosteroids and  avoidance  of  possible  triggers. s.  aurues colonization is a common complication. during exacerbation,  intensification  of treatment  is needed  to relieve   the  child   from   the   miserable   symptoms   of pruritus   and  sleep  disturbance.   systemic   antibiotics agains...

BACKGROUND The pattern of eczema is altered by geography, habits of people and environmental factors and regional variation in skin structure and function. AIMS Our study was done to estimate frequency and patterns of lower leg and foot eczemas. METHODS A total of 200 patients with various types of lower leg and foot eczemas were recruited over a period of 2 years. Demographic and clinical ...

introduction: papillon-lefèvre syndrome(pls) characterized by palmoplantar hyperkeratosis is a rare autosomal recessive genetic disorder with rapidly progressive periodontitis and premature loss of both deciduous and permanent teeth. in this study, we report the clinical and radiographic features of papillon-lefèvre syndrome in an 11- year-old girl and we also discuss the history and various th...

OBJECTIVE To inform the development of a core outcome set for eczema by engaging with people with eczema and parents of children with eczema to understand their experiences and understanding of the concept 'eczema control'. DESIGN 37 participants took part in a total of six semi-structured online focus groups held in a typed chatroom with 5-7 participants per group. Three groups involved adul...

Mal de Meleda is a rare transgressive palmoplantar keratoderma with an estimated prevalence of 1 in 100,000 individuals. It was first described in 1826 by Stulli on the island of Mljet. Its autosomal recessive inheritance was described in 1938, and the defective gene was localized to chromosome 8 qter in 1998. Clinical features are the result of abnormal palmoplantar keratinization and include ...

In some patients, psoriasis appears refractory to many treatments, particularly when the disease is confined to some specific body regions. In this respect, palmoplantar psoriasis and palmoplantar pustulosis are possibly related conditions in their immunopathomechanisms involving Il-12, IL-23, and Th17. Nail psoriasis and scalp psoriasis are two other particular psoriasis manifestations. Accord...