Inferior temporal cortex (IT) neurons have reduced receptive field sizes in complex natural scenes. This facilitates the read-out of information about individual objects from IT, but raises the question of whether more than the single object present at the fovea is represented by the firing of IT neurons, as would be important for whole scene perception in which several objects may be located w...

Acne rosacea is a relatively common disease, which usually manifests in the third and fourth decades of life. It has an inflammatory condition (Papules and pustules) associated with telangiectasis, erythema and sometimes rhinophyma at the end stage of the disease. Pulsed-dye-laser (PDL), which has been designed for treatment of vascular lesions, may be used in treatment of acne rosacea. We pres...

Four young adults with 0.0 logMar acuity participated in this study. The stimulus was based on vertical sinusoidal gratings masked by a circular (for foveal area) or a ring (for parafoveal area). To increase the luminance resolution of the display a bit-stealing technique was used. Four different sets of stimuli were generated, two for exploring the foveal sensitivity and two for the parafoveal...

BACKGROUND Hereditary haemorrhagic telangiectasia (HHT) is an autosomal dominant vascular dysplasia characterised by mucocutaneous telangiectasis, epistaxis, gastrointestinal haemorrhage, and arteriovenous malformations in the lung and brain. Causative mutations for HHT have been identified in two genes, endoglin and ALK1, which encode proteins involved in serine-threonine kinase signalling in ...

Coats' disease is an idiopathic, ophthalmic condition characterized by retinal telangiectasis, intraretinal and subretinal exudation, which can lead to retinal detachment. It is mostly unilateral, progressive and affects mainly males during childhood, although adult cases have also been described. In this review, we make an update of the literature about Coats' disease, emphasizing on diagnosis...

PURPOSE Studies using optimized entoptic viewing of the parafoveal retinal vasculature have shown that normal subjects see their own capillaries with greater detail in the fovea than seen typically in fluorescein angiography. The authors have extended these investigations to persons with diabetes to evaluate the sensitivity, specificity, and accuracy with which they can detect and locate their ...

PURPOSE To investigate whether individuals, with no family history of ataxia telangiectasia (AT), in whom idiopathic or radiation-induced ocular telangiectasia developed are carriers of ATM gene mutations. METHODS The ATM cDNA from lymphoblastoid cell lines established from 16 patients with idiopathic retinal or choroidal telangiectasia and 14 patients with radiation-induced telangiectasia af...