Paragangliomas are tumors arising from neuroepithelial cell groups called paraganglia, first reported by Alfred Kohn in 1903 [1]. They are benign tumors. The paraganglia are subdivided into two groups: one formed by the adrenal medulla and the other by the extraadrenal paraganglia. From the first one arises, the typical pheocromocytoma. The most common site for extra-adrenal paragangliomas is t...

Paragangliomas/pheochromocytomas comprise rare tumors that arise from the extra-adrenal paraganglia, with an incidence of about 2 to 8 per million people each year. Approximately 40% of cases are due to genetic mutations in at least one out of more than 30 causative genes. About 25-30% of pheochromocytomas/paragangliomas develop under the conditions of a hereditary tumor syndrome a third of whi...

paragangliomas are extra-adrenal counterparts of pheochromocytomas and are found at various anatomical sites such as the retroperitoneum, mediastinum, jugular foramen and carotid bifurcation, the latter two fonns being coined as chemodectomas. the vertebral column, especially the llullbar zone, is one of the rarest sites to be involved by paragangliomas. these lesions may have secretory functio...

Functional paragangliomas of the thoracic spine are uncommon malignancies that require a multidisciplinary therapeutic approach. These catecholamine-secreting tumors increase the risk of life-threatening complications such as hypertension, cardiac arrhythmias and massive bleeding during surgery due to an excessive vascular supply. Appropriate manipulation of functional paragangliomas reduces mo...

Paragangliomas are neoplasms of neural crest origin. In the head and neck, they uncommonly involve the larynx. The distinction between paragangliomas and other neuroendocrine tumors can be difficult. Precise diagnosis is important in order to optimize patient treatment. Diagnosis relies mostly on histopathologic examination followed by immunohistochemistry. Here we report a 77-year-old woman wi...

Paragangliomas are extra-adrenal chromaffin tumours that develop at the expense of neuroectodermal cells of the autonomous nervous system. Retroperitoneal and nonfunctioning forms are very rare. They are often asymptomatic and can reach a substantial size. Treatment usually involves surgery with the goal of total excision. We report the case of a patient who presented with indistinct abdominal ...

BACKGROUND The objective of this study was to report 11 cases of malignant head and neck paraganglioma and to compare their epidemiological, clinical, and genetic characteristics, their natural history and their treatment with those of a series of 131 benign paragangliomas. PATIENTS AND METHODS Retrospective analysis of 142 patients with head and neck paraganglioma managed between 2001 and 20...

1.0 Properties of M0,n ⊂ M0,n. (1) M0,n has a natural moduli interpretation, namely it is the moduli space of stable n-pointed rational curves. (2) Given power series f1(z), . . . , fn(z) which we think of as a one parameter family in M0,n one can ask: What is the limiting stable n-pointed rational curve in M0,n as z → 0 ? There is a beautiful answer, due to Kapranov [Kapranov93a], in terms of ...

INTRODUCTION Collections of neuroendocrine cells dispersed throughout the body are known as paraganglia and the tumor arising from these paraganglia are known as paragangliomas. Paragangliomas located along side the aorta are associated with the pheochromocytoma and they secrete and store catecholamines. CASE REPORT We reported a 29-year-old woman with episodes of headache, palpitations, dizz...