نتایج جستجو برای: pathogenesis clinical implications

تعداد نتایج: 1570872  

The colorectal cancer (CRC) subtyping consortium has unified six independent molecular classification systems, based on gene expression data, into a single consensus system with four distinct groups, known as the consensus molecular subtypes (CMS); clinical implications are discussed in this review based on articles relevant to the CMS of CRC indexed in PubMed as well as the authors’ own ...

Journal: :International Journal of Applied Pharmaceutics 2021

Acne vulgaris (AV) occurs in more than 80% of dermatological cases adolescents and young adults affects the quality life. Oral isotretinoin, a metabolite product vitamin A, is well-known to be most effective treatment for severe nodulocystic AV moderate that does not respond other therapeutic modalities. Thus, this literature review was conducted explain mechanism action, effectiveness, contrai...

Journal: :Journal of the American Academy of Dermatology 2016

Journal: :DMW - Deutsche Medizinische Wochenschrift 2004

Journal: :Nihon Shuchu Chiryo Igakukai zasshi 2009

Journal: :World journal of gastroenterology 2016
Mhairi C Donnelly Peter C Hayes Kenneth J Simpson

Acute liver failure is a rare and devastating clinical condition. At present, emergency liver transplantation is the only life-saving therapy in advanced cases, yet the feasibility of transplantation is affected by the presence of systemic inflammation, infection and resultant multi-organ failure. The importance of immune dysregulation and acquisition of infection in the pathogenesis of acute l...

Journal: :JEADV Clinical Practice 2023

The severe autoimmune blistering disease pemphigus vulgaris (PV) is most probably mainly due to autoantibodies directed against desmosomal components of the epithelium, disrupting cell-cell adhesion. precise mechanisms underlying development are still unknown, and immunosuppressive medications such as corticosteroids, which linked potentially serious adverse effects, mainstay treatment. Ethnic ...

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