نتایج جستجو برای: pathologic type
تعداد نتایج: 1380746 فیلتر نتایج به سال:
Tauopathies with parkinsonism represent a spectrum of disease entities unified by the pathologic accumulation of hyperphosphorylated tau protein fragments within the central nervous system. These pathologic characteristics suggest shared pathogenetic pathways and possible molecular targets for disease-modifying therapeutic interventions. Natural history studies, for instance, in progressive sup...
OBJECTIVE To determine ways to improve diagnostic accuracy of multiple system atrophy (MSA), we assessed the diagnostic process in patients who came to autopsy with antemortem diagnosis of MSA by comparing clinical and pathologic features between those who proved to have MSA and those who did not. We focus on likely explanations for misdiagnosis. METHODS This is a retrospective review of 134 ...
Pathologic ocular neovascularization commonly causes blindness. It is critical to identify the factors altered in pathologically proliferating versus normally quiescent vessels to develop effective targeted therapeutics. MicroRNAs regulate both physiological and pathological angiogenesis through modulating expression of gene targets at the posttranscriptional level. However, it is not completel...
BACKGROUND Pathologic signs in orbital phlebographies have been reported in various neurological diseases. PURPOSE To study if pathologic signs in orbital phlebography may be markers of inflammation primarily affecting intracranial capillaries, which would cause intracranial hypertension. MATERIAL AND METHODS Two groups with different intracranial cerebrospinal fluid pressures (Pcsf) were c...
PURPOSE To evaluate the accuracy of radiologic tumor size for making decisions regarding nephron-sparing surgery of localized renal cell carcinomas (RCCs), we compared tumor size measured by a preoperative radiologic modality with that measured in the pathologic specimen. MATERIALS AND METHODS Between January 2003 and December 2007, a total of 186 patients with pT1 or pT2 RCC underwent radica...
a comparison of virulence of intraperitoneal infection of burkholderia mallei strains in guinea-pigs
male guinea pigs show high susceptibility to burkholderia mallei and have been used as animal models in glanders studies. the purpose of our study was to elucidate glanders comparative pathogenesis in guinea pigs. we present here the histological changes and bacterial isolation that develop over time in guinea pigs inoculated intraperitoneally (ip) with two strain of b. mallei. ten male guinea ...
the aim of this study was to assess the value of 99mtc-hexakis-2-methoxyisobutylisonitrile (mibi) scintigraphy in patients with clinical and radiologic features of primary or metastatic musculoskeletal tumors. methods: the scintigraphic findings for 84 patients were compared with the surgical and histologic findings. each patient underwent three-phase bone scan with 99mtc-methylene diphosphonat...
HYPOTHESIS Core-needle biopsy (CNB) and fine-needle aspiration (FNA) play an important role in the initial diagnosis of breast cancer. However, CNB might alter the size of the tumor, which might subsequently change its pathologic stage and thus affect the decision about adjuvant chemotherapy. PATIENTS Between January 2000 and May 2002, we studied 291 patients with invasive carcinoma lesion in...
central nervous system atypical teratoid/rhabdoid tumor during infancy is a rare, highly aggressive tumor most commonly seen in the cerebellar area. herein we describe the case of a 4-month-old baby who presented with convulsions. pathologic examination of her cerebellar mass showed an atypical teratoid/rhabdoid tumor. the patient died 5 days after surgery despite complete excision of the mass ...
We report analytic and consensus processes that produced recommendations for neoadjuvant pathologic stage groups (ypTNM) of esophageal and esophagogastric junction cancer for the AJCC/UICC cancer staging manuals, 8th edition. The Worldwide Esophageal Cancer Collaboration provided data for 22,654 patients with epithelial esophageal cancers; 7,773 had pathologic assessment after neoadjuvant thera...
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