Establishment of water quality criteria (WQC), intended to protect aquatic life, continues to rely principally on water hardness (i.e. Ca(2+)) for lead (Pb) despite growing evidence that other chemical parameters also strongly influence toxicity. To more clearly define the water chemistry parameters mediating Pb toxicity, we evaluated the effects of hardness as CaSO(4) and dissolved organic car...

It has been reported that lead (Pb) exposure enhances interleukin (IL)-4 and inhibits interferon-gamma (IFNgamma) production in wild-type (WT) BALB/c mice. Here, we examined Pb effects on immunity in IFNgamma knockout (KO) mice. Lead significantly enhanced serum IgG1 anti-keyhole limpet hemocyanin (KLH) levels in WT mice compared to the controls; Pb also increased serum IgG2a anti-KLH levels, b...

A foam-like mesoporous polymer of melamine-formaldehyde (mPMF) was synthesized and further deposited on disposable screen-printed electrodes (SPEs) for the electroanalysis of Pb(2+) ions in blood. Investigations indicate that the prepared mPMF is ultrastable in water, showing a mesoporous structure and an amine-rich composition, as characterized by electronic microscopy images and IR spectra. I...

Lead exposure represents a medical and public health emergency, especially in children consuming high amounts of lead-contaminated flake paints. It may also cause hematological effects to people of all ages. Recent studies in our laboratory have indicated that apoptosis may be associated with the lead-induced oxidative stress and DNA damage. However, the mechanisms underlying its effect on lymp...

OBJECTIVE To perform a randomized trial to determine whether there is cardiovascular disease (CVD) risk reduction from a plant-based (PB), no-added-fat diet and the American Heart Association (AHA) diet in children. STUDY DESIGN A 4-week (April 20, 2013 to May 18, 2013), prospective randomized trial was undertaken in a large, Midwestern hospital system's predominantly middle class outpatient ...

Unusually radiogenic Pb has been found in sediments of a portion of the Ashtabula River (80 o 48’ W, 41 o 54’ N) near its confluence with Lake Erie. Pb isotopic compositions have been determined by quadrupole ICPMS, revealing that the Pb results from mixing of three sources: crustal Pb, common Pb from industrial pollutant sources, and highly radiogenic Pb associated with U-containing accessory ...

The use of lead bullets and shot at shooting ranges is under increasing scrutiny as a potentially significant source of Pb pollution. This study assessed Pb contamination in the soils of two shooting ranges (TRR and MPR) in Florida. Soil samples were collected from the two ranges and analyzed for total Pb to determine Pb contamination. Selected spent bullets and berm soil samples were mineralog...

Lead (Pb) concentrations and isotopic compositions from soils, dusts and aerosols from public land and residential lots adjacent to the copper and Pb mine and smelter at Mount Isa, Australia, were examined to understand the sources and risks of environmental Pb exposure. Urban soil samples contain elevated Pb concentrations (mean 1560 mg/kg), of which 45-85% of the Pb is bioaccessible. The Pb i...

The existence of ancient rocks in present mid-ocean ridges have long been observed but received less attention. Here we report the discovery of zircons with both reasonably young ages of about 5 Ma and abnormally old ages of approximate 180 Ma from two evolved gabbroic rocks that were dredged from the Southwest Indian Ridge (SWIR) in the Gallieni fracture zone. U-Pb and Lu-Hf isotope analyses o...