Peritoneal exÃodate cells (PEC) harvested from mice after i.p. injection of squalene-treated cell wall skeleton of Nocardia rubra (N. rubra-CWS) demonstrated vigorous cytolytic activity in vitro toward tumor target cells. Fractionation of these PEC by adherence to plastic dishes showed that the cytolytic activity in PEC was associated with an adherent phagocytic cell. In duction of the cytolyti...

Peritoneal exudate cells (PEC) harvested from mice after i.p. injection of squalene-treated cell wall skeleton of Nocardia rubra (N. rubra-CWS) demonstrated vigorous cytolytic activity in vitro toward tumor target cells. Fractionation of these PEC by adherence to plastic dishes showed that the cytolytic activity in PEC was associated with an adherent phagocytic cell. Induction of the cytolytic ...

STUDY DESIGN The study was based on porcine posterolateral fusion model. OBJECTIVE The study aims to prove that polyelectrolyte complex (PEC) carrier could enhance the efficacy and safety profile of bone morphogenetic protein-2 (BMP-2). SUMMARY OF BACKGROUND DATA BMP-2 was introduced to enhance posterolateral fusion; however, extremely high doses of this molecule were often used which contr...