PURPOSE Diagnostic imaging, including ionizing radiation modalities, maintains a prominent role in the medical evaluation of patients. There is increasing awareness and need for information across varied sectors about low-level radiation and potential risks. Many medical and scientific organizations have resources discussing radiation risk and management. However, there is no single resource co...

The current version of the International Society of Pediatric and Adolescent Diabetes (ISPAD) guidelines for management of diabetic ketoacidosis (DKA) is largely based on the Lawson Wilkins Pediatric Endocrine Society/European Society of Pediatric Endocrinology (LWPES/ESPE) consensus statement on DKA in children and adolescents published in 2004. This article critically reviews and presents the...

The authors describe a seven-step consensus development process used to create the two most recent editions of the Academic Pediatric Association's (APA's) educational guidelines for pediatric residency. The 1996 (printed) and 2004 (online) editions of the guidelines were designed as flexible tools to help residency programs meet changing accreditation requirements by providing lists of goals a...

Febrile episodes and infections represent important complications during antineoplastic chemotherapy for pediatric neoplastic diseases. In the last years many international association published guidelines for the management of these complications in adults, but no document of this type was prepared for children. One of the major causes of this situation is probably the very low number of pedia...

Introduction: In pediatric patients, titratable infusions often do not follow the standard concentrations used for adults. Dosing is usually weight based and for neonates fluid volumes are often restricted to prevent fluid overload. Thus, pediatric infusion bags are typically custom concentrations tailored to the needs of an individual patient. The physician normally specifies the dose, e.g.., ...

Dose selection is one of the key decisions made during drug development in pediatrics. There are regulatory initiatives that promote the use of model-based drug development in pediatrics. Pharmacometrics or quantitative clinical pharmacology enables development of models that can describe factors affecting pharmacokinetics and/or pharmacodynamics in pediatric patients. This manuscript describes...

Acutely ill and immobilized neonates and children are at risk for pressure ulcers, but a paucity of evidence-based research exists on which to base guidelines for clinical practice. Most prevention and treatment protocols for pressure ulcers in the pediatric population are extrapolated from adult practice. Clinical practice guidelines for prevention and treatment of pressure ulcers that specifi...

OBJECTIVE The Image Gently Campaign of The Alliance for Radiation Safety in Pediatric Imaging seeks to increase awareness of opportunities to lower radiation dose in the imaging of children. Pause and Pulse is the most recent phase of the campaign, addressing methods of dose optimization in pediatric fluoroscopy. CONCLUSION This article discusses 10 steps that can be taken for fluoroscopic do...

The management of pediatric head injuries has evolved over the past decade,and a number of significant advances have been made. Evidence-based guide-lines and algorithms for the management of severe pediatric head injuries have recently been published, and all pediatricians who care for children with severe head injuries should be familiar with these guidelines. It is hoped the guidelines will ...