نتایج جستجو برای: pegylated dendrimers
تعداد نتایج: 9179 فیلتر نتایج به سال:
We investigate the spectral properties of balanced trees and dendrimers, with a view toward unifying improving existing results. Here we find semi-factorized formula for their characteristic polynomials. Afterwards, determine spectra via aforementioned factors. In end, analyze behavior energy dendrimers compute lower upper bound approximations it.
Site-Specific PEGylation of Recombinant Immunotoxin DAB389IL-2: Structural and Functional Assessment
Background: DAB389IL-2 is considered a fusion immunotoxin and it is used for the CTCL therapy. DAB389IL-2 includes of two distinct portions; the catalytic domain of diphtheria toxin and IL-2. DAB389IL-2 duo to the presence of a free cysteine residue (Cys 513 in IL-2 part) is prone to unwanted intramolecular and intermolecular disulfide bonds formation and aggregation problems. Aggregation is co...
Poly(amidoamine)(PAMAM) dendrimers with a cinnamoyl shell were prepared by reacting full generation PAMAM dendrimers (G53.0) with 2-chloroethanol and cinnamoyl chloride, which resulted in densely packed polymerizable unsaturated groups on the periphery. The cinnamoyl shell of the dendrimers dimerized when irradiated under a UV light by using 5-nitroacenaphthylene as an initiator in dilute dimet...
Here, we investigate the effect of the structure (generation) and nature of the surface groups of different polyamidoamine (PAMAM) dendrimers on electron-mediated dissociation, either electron capture dissociation (ECD) or electron detachment dissociation (EDD), and compare the fragmentation with that observed in collision-induced dissociation (CID). ECD and EDD of the PAMAM dendrimers resulted...
the omega polynomial(x) was recently proposed by diudea, based on the length of stripsin given graph g. the sadhana polynomial has been defined to evaluate the sadhana index ofa molecular graph. the pi polynomial is another molecular descriptor. in this paper wecompute these three polynomials for some infinite classes of nanostructures.
Preparation of photo-responsive carbosilane dendrimers bearing 4-phenylazobenzonitrile units on their molecular surface has been accomplished, and their both photo and thermal behaviors have also been characterized. These functional dendrimers suggest that the apparent molecular sizes of the cis-isomers are smaller than those of the corresponding trans-isomers, since the molecular diameter of t...
[reaction: see text] We have designed and synthesized difunctionalized dendrimers containing two donors in the periphery and an acceptor at the core to serve as scaffolds for comparison with linear analogues to investigate the advantage of dendritic scaffolds for energy and charge transfer. Comparison of these dendrimers with the fully decorated dendrimers provides information on the advantage ...
Dendrimer-encapsulated Pt nanoparticles can be synthesized by Pt2þ coordination with dendrimers followed by reduction. In the present study, we have systematically investigated the coordination kinetics of PtCl4 2 with fourth-generation hydroxyl-terminated poly(amidoamine) (PAMAM G4-OH) dendrimers using UV vis spectroscopy measurements. Our experimental investigation clarifies that Pt2þ coordin...
This paper describes an investigation of the uptake of Cu(II) by poly(amidoamine) (PAMAM) dendrimers with an ethylenediamine (EDA) core in aqueous solutions. We use bench scale measurements of proton and metal ion binding to assess the effects of (i) metal ion-dendrimer loading, (ii) dendrimer generation/terminal group chemistry, and (iii) solution pH on the extent of binding of Cu(II) in aqueo...
Dendrimers are a new class of polymeric materials. They are highly branched, monodisperse macromolecules. The structure of these materials has a great impact on their physical and chemical properties. As a result of their unique behaviour dendrimers are suitable for a wide range of biomedical and industrial applications. The paper gives a concise review of dendrimers' physico-chemical propertie...
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