نتایج جستجو برای: peptide receptor radionuclide therapy
تعداد نتایج: 1363778 فیلتر نتایج به سال:
Introduction: Over expression of selected peptide receptors in human tumors has been shown to represent clinically relevant targets for cancer diagnosis and therapy. The aim of this work was to investigate Neuropeptide Y (NPY) as a new radiopharmaceutical for diagnosis of breast cancer. Methods: A neuropeptide Y analogues with Y1 receptor preference and agonistic p...
INTRODUCTION: Medullary carcinoma is a rare malignant neuroendocrine tumor of the thyroid gland. (MTC) has no specific clinical symptoms. Due to absence symptoms, disease usually diagnosed at stage metastatic lesions regional lymph nodes, and sometimes, internal organs. The five- ten-year survival after detection distant metastases 25% 10%, respectively. OBJECTIVE: To analyze available foreign ...
introduction: somatostatin receptors expressed on a wide range of human tumors, are potential targets for the peptide receptor radionuclide therapy (prrt). in this study, 177lu-[dota-dphe1, tyr3]octreotide (177lu-dotatoc) as an agent for prrt was prepared and its biodistribution was studied in rats. methods:the best condition for the preparation of the 177lu-dotatoc radiolabeled complex was det...
UNLABELLED Renal toxicity associated with small-molecule radionuclide therapy has been shown to be dose-limiting for many clinical studies. Strategies for maximizing dose to the target tissues while sparing normal critical organs based on absorbed dose and biologic response parameters are commonly used in external-beam therapy. However, radiopharmaceuticals passing though the kidneys result in ...
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