INTRODUCTION Infectious complications and especially anastomotic leakage (AL) severely impede the recuperation of patients following colorectal cancer (CRC) surgery. When the normal gut barrier fails, as in AL, pathogenic microorganisms can enter the circulation and may cause severe sepsis which is associated with substantial mortality. Moreover, AL has a negative impact on the CRC prognosis. S...

CONTEXT Perioperative antibiotics are widely used to improve the outcomes of endoscopic sinus surgery. OBJECTIVE The aim of this study was to summarize the evidence on the effect of perioperative antibiotic prophylaxis on outcomes of endoscopic sinus surgery. DATA SOURCES AND REVIEW METHODS We searched electronic databases from inception through May 2011 for any relevant clinical trials or ...

Local antibiotic guidelines should comply with national on perioperative prophylaxis to adequately reduce surgical site infections in high-risk oral and maxillofacial (OMF) operations. To inform committees opportunities for improvement, a survey was sent twenty-one OMF surgery departments the Netherlands that performed more extensive procedures. We determined (1) local recommendations antisepti...

conclusions the current study revealed that 44% of those who received prophylaxis did not need it. in the patients who received antibiotics, the most common mistakes were antibiotic selection followed by prolonged prophylaxis (> 24 hours) and excess dose. results of the total 8586 patients who took antibiotics for preventive purposes, 4815 (56%) required antimicrobial prophylaxis, and 3771 (44%...

materials and methods this cross-sectional descriptive analytical study was carried out in hamadan in 2011. ninety gdps participated in this study and filled out a questionnaire. one-way anova andchi-squared test were used for statistical analysis of data. results the knowledge levels of gdps about cardiac diseases, dental procedures requiring prophylaxis and endocarditis prophylaxis regimens w...

introduction: infectious endocarditis might occur by oral microbial flora subsequent to dental procedures leading to bleeding in the oral cavity. therefore, the dental practitioner should be able to prescribe appropriate antibiotics in the prophylactic measures against bacterial endocarditis during dental procedures. the aim of this study was to evaluate the knowledge of general dental practiti...

Background: Identifying risk factors for surgical site infection (SSI) after appendectomies could be useful in focusing prevention programs. Objective: The current study aimed to identify the risk factors associated with SSI in a cohort of patients from a single center in Western Qatar. Methods: This cross-sectional study was carrie...

OBJECTIVE The Surgical Care Improvement Project (SCIP) established surgical antibiotic prophylaxis guidelines as part of a national patient safety initiative aimed at reducing surgical complications such as surgical site infection (SSI). Although these antibiotic prophylaxis guidelines have become well established in surgical patients, they remain largely unstudied in patients with injury from ...

BACKGROUND Surgical site infections are the most common postoperative complications and frequently cause morbidity and mortality. Different antibiotic regimens were evaluated as prophylaxis in wound infection following elective surgical procedures. Prophylactic antibiotics should be given to cover the "decisive period" which is a period after incision to mobilization of host defenses thus preve...

We investigated the effects of implementation of an institution-wide screening and decolonization protocol on the rates of deep surgical site infections (SSIs) in patients undergoing primary knee and hip arthroplasties. 2058 patients were enrolled in this study: 1644 patients in the treatment group and 414 in the control group. The treatment group attended preoperative admission testing (PAT) c...