Background Context: Minimally Invasive Transforaminal Lumbar Interbody Fusion (MI-TLIF) is becoming an increasingly popular vehicle for lumbar fusion procedures. Data suggests that MI-TLIF results in decreased blood loss and operative time with lower complication rates and equivalent patient-reported outcome measures (PROMs) compared to open TLIF. However, literature has shown that obese patien...

PATIENTS WITH SEVERE PERIPHeral vascular disease frequently haveunderlyingcoronaryartery disease. Hence, patients undergoing major vascular surgery are at increased risk for cardiac complications during or shortly after surgery. Appropriatepatientmanagement then includes assessment of the perioperative cardiac risk, as well as strategies to reduce this risk. Several investigations demonstrated ...

PATIENTS WITH SEVERE PERIPHeral vascular disease frequently haveunderlyingcoronaryartery disease. Hence, patients undergoing major vascular surgery are at increased risk for cardiac complications during or shortly after surgery. Appropriatepatientmanagement then includes assessment of the perioperative cardiac risk, as well as strategies to reduce this risk. Several investigations demonstrated ...

During a 4-year multicenter cooperative study of acquired factor VIII inhibitors in persons with hemophilia A. new inhibitors were detected in 31 of 1 .306 patients who entered the study without an inhibitor or the history of an inhibitor. The incidence of new inhibitors was eight per 1 .000 patient-years of observation. The factor Vlll:C level before inhibitor development was 0.03 U/mi in 29 m...

BACKGROUND Total knee arthroplasty is an effective treatment when nonsurgical treatments fail, but it is associated with risk of complications which may be increased in advanced age. The purpose of this study was to quantify age-related differences in perioperative morbidity and mortality after total knee arthroplasty through systematic review of existing literature. METHODS PubMed, the Cochr...

Dr. Januzzi and colleagues in a recent study (1) published in the Journal suggest replacement of creatine kinase-MB fraction (CKMB) with serum troponin testing for postoperative evaluation of the cardiac surgical patient. An important point to remember is the release pattern of these markers. Although the rise (CK-MB 4 to 8 h; CK-MB isoform 2 to 6 h; cardiac troponin I [cTnI] 4 to 6 h; cardiac ...

Dr. Januzzi and colleagues in a recent study (1) published in the Journal suggest replacement of creatine kinase-MB fraction (CKMB) with serum troponin testing for postoperative evaluation of the cardiac surgical patient. An important point to remember is the release pattern of these markers. Although the rise (CK-MB 4 to 8 h; CK-MB isoform 2 to 6 h; cardiac troponin I [cTnI] 4 to 6 h; cardiac ...

conclusions treatment strategies in acquired hemophilia are based on two major objectives. during the acute stage, effective control of bleeding is critical. the ultimate therapeutic goal during the subacute phase is the elimination of the inhibitors targeting factor viii. here, we present this case and will review current literature regarding therapeutic approaches to this rare condition in th...