6 ORIGINAL PAPERS 7 ABBREVIATIONS 8 INTRODUCTION 1. Clinical background and epidemiology 9 2. Pathophysiology of spinal cord and peripheral nerve injury 2.1. Spinal cord 9 2.1.1. Acute and sub-acute spinal cord injury 10 2.1.2. Chronic spinal cord injury 11 2.2. Peripheral nerve 11 3. Regeneration following spinal cord and peripheral nerve injury 3.1. Regeneration following spinal cord injury 1...

tooth pulpal nerves include sympathetic and sensory nerves that originate from trigeminal ganglion .from the terminal of these sensory nerves neuropeptides are secreted that are neuromodulators and neurotransmitters. one of them is cgrp (calcitonin gene-related protein) which has a vasodilatory effect on pulpal vessels. near abscess and moderate injuries, this neuropeptide can lead to neural fi...

INTRODUCTION Recent evidence suggests that the implantation of bone marrow-derived mesenchymal stem cells improves peripheral nerve regeneration. In this study we aimed to investigate whether adipose-derived stem cells (ADSCs) can be used for peripheral nerve repair. MATERIAL AND METHODS In a rat model, nerve regeneration was evaluated across a 15 mm lesion in the sciatic nerve by using an ac...