Observations are reported on the changes which occurred in excised rabbit and human skin after mild trauma and incubation at body temperature. These changes resembled those of chronic inflammation, in that perivascular and diffuse infiltration by histiocytes occurred in the corium and subcutaneous tissue, but they developed within a few hours. The experiments have shown that even after removal ...

Rhinoscleroma was discovered in 1870 by von Hebra (1) who considered it an unusual form of skin cancer. Geber (2) later characterized the lesion as a chronic inflammatory process accompanied by perivascular cellular infiltration and connective tissue proliferation. Mikulicz (3) clearly described the histological picture including the diagnostic "foam" or "lace" cells which have been named after...

The cellular reaction in cardiac homografts was observed mainly in the perivascular areas and in the subepicardial and subendocardial layers. All the valvular structures were involved by the cellular infiltration, but the aortic and pulmonary cusp changes were less severe. Although the vascular changes seemed to be severe, yet, for unknown reasons, some vascular segments and consequently some m...

We herein report an autopsy case of relapsing polychondritis encephalitis coexisting with a Lewy body pathology and also review previous autopsy cases. A 59-year-old man exhibited a tremor of the right hand, small-steppage gait and bradykinesia. Five years later, he presented with relapsing auricular chondritis and scleritis and subsequently showed exacerbation of extrapyramidal symptoms. A his...

© 2010 The Authors. doi: 10.2340/00015555-0835 Journal Compilation © 2010 Acta Dermato-Venereologica. ISSN 0001-5555 Livedo vasculopathy (LV) is a chronic recurrent disease affecting the lower extremities, clinically developing livedo reticularis, purpuric macules, painful ulcers, hyperpigmentation and atrophic scars (1). Histopathologically, there are segmental hyalinization and thrombosis of ...

Leukaemic infiltration of the lungs may occur in acute myeloid leukaemia (AML). Pulmonary infiltrates are usually microscopic and invariably associated with hyperleucocytosis. Four AML patients with respiratory symptoms and low leucocyte counts underwent standard chest radiography, bronchoscopy with bronchoalveolar lavage and high-resolution computerized tomography (HRCT) of the lungs. HRCT sca...

A mixture of ketamine, xylazine, and butorphanol was inadvertently injected into the right carotid artery of a 1-year-old alpaca. Injection was followed by a brief period of recumbency and seizure activity. The alpaca recovered, but was euthanatized 72 hr later because of development of progressive neurologic deficits. Pathologic findings were confined to the right cerebrum, meninges, thalamus,...

An evaluation of electrocardiographic tracings as an index of myocar(lial (lamage in survivors of subacute bacterial endocarditis wvas undertaken in a study of 76 fatal cases of the disease. Anatomic changes, plresent in all, inclu(ledl myocarditis, perivascular infiltration and fibrosis, Aschoff bodies, infarets, and intravascular emboli. Electrocardiographic tracings revealed changes which co...

By subcutaneous injection of central nervous tissue emulsified with adjuvants according to Freund's technique it has been possible to induce in the majority of monkeys an acute disseminated encephalomyelitis which is interpreted as an isoimmunization to CNS tissue. Positive reactions occurred only in response to CNS tissue containing white matter; i.e., cerebral white matter, spinal cord (wheth...

An 83-year-old Caucasian Greek man was referred by his general practitioner to the emergency department of the general hospital in Crete because of seizures and agitation. His past medical history was negative for any neurological or medical condition. Electroencephalogram showed a bradyarrhythmic theta activity, without evidence of any focal or other specific abnormality. Magnetic resonance im...