Lower cutoff levels in screening programs have led to an increase in the proportion of detected cases with transient hypothyroidism, leading to increase of the overall incidence of primary congenital hypothyroidism (CH) in several countries. We have performed retrospective evaluation on the data from 251,008 (96.72%) neonates screened for thyroidstimulating hormone (TSH) level in dried blood sp...

OBJECTIVE To evaluate thyroid function in children with Down's syndrome, and to ascertain the presence of a relationship between overt thyroid diseases and congenital anomalies. MATERIAL AND METHOD One hundred and forty Down's syndrome patients, aged from 3 days to 13 years 9 months, were evaluated for karyotype, thyroid functions and the coexistence of congenital anomalies. RESULTS Trisomy...

Abstract Introduction There is no data on the number as well prevalence of congenital hypothyroidism (CH) in Fars province. Hence, we designed this study to analyze latest and possible predictive factors transient permanent CH Method This cross sectional based province screening from 2013 2016. A total 294,214 newborns were screened with 938 confirmed cases CH, which included study. After recal...

Congenital hypothyroidism is the most frequent congenital endocrine disorder and prevent‐ able cause of mental retardation. The remarkable irreversible mental damage can be avoided by the replacement therapy introduced before the age of 3 weeks. Therefore a screening program implemented in the early seventies to pick up the affected babies on the first weeks of life [1,2]. After pilot studies s...

background: the aim of this study was to investigate the relationship between congenital hypothyroidism and several variables using two different adjustment methods. methods: this matched case-control study was conducted in hamadan province, the west of iran, in 2012 enrolling neonates born between 2005 and 2011 and covered by screening program for congenital hypothyroidism. the neonates with t...

Introduction: Congenital hypothyroidism is a preventable cause of intellectual disability in childhood. It one the commonest endocrine conditions encountered neonatal period. Maternal Thyroid Status has long been recognized as having an impact on developing fetus, and more recently family history thyroid dysfunction implicated risk factor congenital (CH). Therefore, this study focused screening...

Congenital hypothyroidism, defined as the functional deficiency of thyroid hormones present at birth, is the most frequent endocrine disorder in pediatric patients with an incidence estimated in 1:2,0004,000 newborns. Significantly, iodide deficiency still remains as the leading cause of hypothyroidism at birth [1]. However, in iodidesufficient countries, a number of recent studies indicates th...