Several growth factors have been used in tissue regeneration therapy. Here we describe the use of an autologous blood clot combined with gelatin for teeth affected by severe periodontitis and vertical root fracture treated using three oral surgical procedures: periodontal flap surgery, intentional tooth replantation (IR), and tooth autotransplantation. Treatment with a blood clot improved the c...

OBJECTIVE This article will review the new concept of regenerative endodontics in the management of immature permanent teeth. The potential role of stem cells to regenerate immature permanent teeth after conservative treatment will be discussed. DATA AND SOURCES Two sets of data source are focused in this review: (i) the characterization of various dental stem cells discovered since 2000 and ...

Stem cells are capable of renewing themselves through cell division and have the remarkable ability to differentiate into many different types of cells. They therefore have the potential to become a central tool in regenerative medicine. During the last decade, advances in tissue engineering and stem cell-based tooth regeneration have provided realistic and attractive means of replacing lost or...

An unerupted supernumerary tooth was attached to the root surface of an unerupted permanent lateral incisor. It was necessary to remove both the supernumerary and the permanent lateral incisor as a single unit. The permanent lateral incisor was separated from the supernumerary and placed back into the original developmental crypt. The replanted lateral incisor erupted normally one year later. W...

Traumatic injury to a primary tooth and/or a bone fracture has the potential to damage the underlying permanent tooth germ which may disturb its development. The extent of the malformation depends on the developmental stage of the permanent tooth and the intensity of the trauma. The presence of infection may be a predictive factor for these abnormalities. Open surgical procedures can also poten...

The ultimate goal of endodontics therapy is the regeneration of tooth supporting tissues. This case study evaluated whether the transplantation of autologous dental pulp stem cells with chitosan scaffold into pulpless root canals could mediate pulp regeneration in human mature teeth. The dental pulp stem cells isolated from the patient`s pulp tissue. The cells were then seeded onto a chitosan s...

BACKGROUND Tooth mortality is important in evaluating dental care as tooth loss is a reflection of cumulative effects of past disease and treatment practices. AIM The aim of this study is to analyze the pattern of tooth mortality among pediatric dental patients treated at the University of Benin Teaching Hospital, Benin City, Nigeria. SUBJECTS AND METHODS This was a retrospective study of p...

Background: Tooth mortality is important in evaluating dental care as tooth loss is a reflection of cumulative effects of past disease and treatment practices. Aim: The aim of this study is to analyze the pattern of tooth mortality among pediatric dental patients treated at the University of Benin Teaching Hospital, Benin City, Nigeria. Subjects and Methods: This was a retrospective study of pa...

stem cell-based therapy has great potential in treating health conditions including cardiovascular, autoimmune, type i diabetes, neurodegenerative and bone and cartilage diseases also in spinal cord injuries, malformations and cancer. in addition to their potential use to treat systemic diseases, stem cell-based therapy also provides a powerful tool to treat oral and dental diseases such as cra...