BACKGROUND Current radiographic prognosticators of the outcome of Perthes disease can only be applied after femoral head deformity has occurred. Quantification of femoral head perfusion using the gadolinium-enhanced subtraction magnetic resonance imaging (MRI) technique may serve as an early prognosticator of outcome. The purposes of this study were 2-fold: (1) to develop a reliable method to q...

We studied the natural history of Perthes' disease in 62 children in whom the onset of symptoms was in adolescence. Three patterns of disease were noted, namely, late-onset pattern, segmental collapse, or destructive with failure of revascularisation. In the late-onset pattern, the disease followed the sequence of healing seen in younger children, but adequate epiphyseal remodelling did not occ...

During the last decade it has become evident that Perthes' disease can no longer be considered as a local ischaemic disorder in an otherwise normal child.1-3 The affected child's growth and development are unusual in several respects, namely (figure): * Bone aFe3-5 * Stature 8 and growth velocity9 * Disproportionate skeletal growth6 7 * Hormonesl'-2 * Congenital anomalies and defects13 14 * The...

Introduction: Legg-Calve-Perthes Disease (LCPD) is a complex condition with limited understanding about its healing process. The mechanism of LCPD believed to differ significantly from adult hip avascular necrosis (AVN), thus necessitating an exploration into alternative mechanisms. Our research focused on these mechanisms using review histologic specimens, thorough literature review, and trans...