The aim of the research work was to chemically modify guargum (GG) as a pH sensitive co-polymer and formulating intestinal targeting ESO nanoparticles (NPs) using the synthesized co-polymer. Poly acrylamide-grafted-guar gum (PAAm-g-GG) co-polymer was synthesized by free radical polymerization. Chemical modification of PAAm-g-GG by alkaline hydrolysis results in formation of a pH-sensitive co-po...

The amino acid composition and the physicochemical and functional properties of quinoa protein isolates were evaluated. Protein isolates were prepared from quinoa seed by alkaline solubilization (at pH 9, called Q9, and at pH 11, called Q11) followed by isoelectric precipitation and spray drying. Q9 and Q11 had high levels of essential amino acids, with high levels of lysine. Both isolates show...

Struvite is known to form a hard scale in specific areas of wastewater treatment plants. Besides causing problems; struvite can also be used as a fertilizer. Good and reliable solubility data is essential for controlling the crystallisation of struvite. One of the important factors that affect the crystallisation of struvite is solution pH. Therefore, this study was undertaken to investigate in...

BACKGROUND AND AIMS Fatty foods are commonly reported to aggravate gastro-oesophageal reflux symptoms. In this study the hypothesis that fat provokes reflux by stimulating transient lower oesophageal sphincter relaxations via small intestinal receptors was investigated. METHODS In 12 healthy volunteers and 11 patients with reflux oesophagitis, oesophageal motility and pH were measured over 30...

Instrumental analysis of vermicompost with the help of modern technologies provides essential information on its maturity, before it can be used for agricultural application. Nowadays, vermicompost is considered as a promising organic alternative to chemical fertilizers in agriculture and horticulture. The objectives of this review are to summarize the sophisticated instrumental techniques such...

We report the successful preparation of reinforced electrospun nanofibers and fibrous mats of polyvinyl alcohol (PVA) via a simple and inexpensive method using stable tannic acid (TA) and ferric ion (Fe+++) assemblies formed by solution mixing and pH adjustment. Changes in solution pH change the number of TA galloyl groups attached to the Fe+++ from one (pH < 2) to two (3 < pH < 6) to three (pH...

How ocean acidification affects marine life is a major concern for science and society. However, its impacts on encrusting biofouling communities, that are both the initial colonizers of hard substrata and of great economic importance, are almost unknown. We showed that community composition changed significantly, from 92% spirorbids, 3% ascidians and 4% sponges initially to 47% spirorbids, 23%...

To explore the role of the Na-H antiport in essential hypertension, we studied the kinetics of cytosolic pH and external sodium activation of this transport system in platelets from 65 normotensive and essential hypertensive subjects on and off antihypertensive medications. Subjects included both blacks and whites, as well as men and women. The fluorescent dye 2'7-bis(carboxyethyl)-5,6-carboxyf...

The present work focused on the design of drug delivery system based on an amphiphilic and pH-sensitive hydrogel. The hydrogels were prepared via graft copolymerization of acrylic acid (AA) onto chitosan backbones by a free radical polymerization technique. The structure and surface morphology of the hydrogels were characterized by FTIR and SEM, respectively. The swelling and pH-sensitive prope...

The present study was designed to examine the activity of the sodium-independent chloride-bicarbonate anion exchanger and the sodium-proton exchanger in erythrocytes of 30 normotensive and 35 hypertensive subjects and its relation to the previously reported decrease in erythrocyte pH. Erythrocyte cytosolic pH was measured by the pH-sensitive fluorescent probe 2'-7'-bis(2-carboxyethyl)- 5(6)-car...