Polyvinyl alcohol (PVA) hydrogels are materials for potential use in burn healing. Silver nanoparticles can be synthesized within PVA hydrogels giving antimicrobial hydrogels. Hydrogels have to be swollen prior to their application, and the common medium available for that in hospitals is saline solution, but the hydrogel could also take up some of the wound's fluid. This work developed gamma-i...

Stimuli-responsive drug delivery systems are urgently required for injectable site-specific and release of drugs in a controlled manner. For this purpose, we developed novel pH-sensitive, biodegradable, antimicrobial hydrogels from bio-macromolecule pectin, polyvinylpyrrolidone (PVP), 3-aminopropyl (diethoxy)methyl silane (3-APDEMS), sepiolite clay via blending solution casting technique. The p...

Here we present the concept of metallophilic hydrogels, supramolecular systems in which the gelator species are metal-thiolates that self-assemble through metallophilic attractions. The principle is applied for a small drug, the mucolytic agent N-acetyl-l-cysteine (NAC), which readily forms hydrogels in the presence of Au(iii), Ag(i) and Cu(ii) salts. The resulting transparent hydrogels present...

A novel versatile biocompatible hydrogel of whey protein isolate (WPI) and two types tannic acid (TAs) was prepared by crosslinking WPI with TAs in a one-step method at high temperature for 30 min. is one common protein-based preparation which used formation. The obtained WPI-TA hydrogels were disc form retained their integrity after sterilization autoclaving. Two TA preparations differing mole...

Chemistry of Materials is published by the American Chemical Society. 1155 Sixteenth Street N.W., Washington, DC 20036 Article Ultrathin Layer-by-Layer Hydrogels with Incorporated Gold Nanorods as pH-Sensitive Optical Materials Veronika Kozlovskaya, Eugenia Kharlampieva, Bishnu P. Khanal, Pramit Manna, Eugene R. Zubarev, and Vladimir V. Tsukruk Chem. Mater., 2008, 20 (24), 7474-7485 • DOI: 10.1...

A novel crosslinked hydrogel was prepared from sodium carboxymethyl cellulose (CMC) and hydroxyethyl cellulose (HEC) using ammonium persulfate as an initiator and methylenebisacrylamide as a crosslinker for drug delivery. The chemical structure of the copolymer was characterized by Fourier transform infrared spectroscopy and X-ray diffraction, and the morphology was observed under scanning elec...

In this study, a new pH-/temperature-sensitive, biocompatible, biodegradable, and injectable hydrogel based on poly(ethylene glycol)-poly(amino carbonate urethane) (PEG-PACU) copolymers has been developed for the sustained delivery of human growth hormone (hGH). In aqueous solutions, PEG-PACU-based copolymers existed as sols at low pH and temperature (pH 6.0, 23 °C), whereas they formed gels in...