نتایج جستجو برای: phencyclidine
تعداد نتایج: 1765 فیلتر نتایج به سال:
We evaluated the use of straw compost and remediated soil as inocula for bioremediation of chlorophenol-contaminated soil. The in situ biotransformation of pentachlorophenol (PCP) and mineralization of radiolabeled [U-(sup14)C]PCP by straw compost and remediated soil were studied under field-simulating conditions before and after 3 months of adaptation with PCP in a percolator. After PCP adapta...
The effects of methamphetamine, phencyclidine and delta9-tetrahydrocannabinol on responding under differential reinforcement of low rate schedules (DRL schedules) were studied under three different DRL time requirements. Under the DRL schedules studied, rats were required to space responses at least a minimum, but not more than a maximum, time interval apart. The time intervals between response...
A study of the relation between the psychotropic activity and the antagonism to acetylcholine observed for some heterocyclic amino esters and compounds of the phencyclidine series suggests some common molecular structural requirements for their properties. Criteria obtained from quantum mechanical calculations of acetylcholine-like molecules indicate that their molecular reactivity with the cho...
Cells of many tissues acquire cellular asymmetry to execute their physiologic functions. The planar cell polarity system, first characterized in Drosophila, is important for many of these events. Studies in Drosophila suggest that an upstream system breaks cellular symmetry by converting tissue gradients to subcellular asymmetry, whereas a downstream system amplifies subcellular asymmetry and c...
Cytochrome P450 (P450) 2B5 was recently found to be functionally distinct from three other rabbit P450 2B forms, based on androstenedione hydroxylase activities. In this investigation, we examined the frequency of the P450 2B5-null phenotype and the functional consequences of polymorphic P450 2B5 expression in hepatic microsomes from phenobarbital-treated rabbits. Four of the 10 animals examine...
The interaction of an optically pure benzomorphan opiate, (-)-N-allyl-N-normetazocine [(-)-ANMC], with the nicotinic acetylcholine receptor from Torpedo electroplaque was studied by using radioligand binding and affinity labeling. The binding was complex with at least two specific components having equilibrium dissociation constants of 0.3 microM and 2 microM. The affinity of the higher affinit...
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