abstract background: autosomal dominant polycystic kidney disease (adpkd) is an inherited disorder with genetic heterogeneity. up to three loci are involved in this disease, pkdi on chromosome 16p13.3, pkd2 on 4q21, and a third locus of unknown location. methods: here we report the first molecular genetic study of adpkd and the existence oflocus heterogeneity for adpkd in the iranian population...

introduction lamb production is the largest part of income in sheep industry. therefore, the mortality rate of lambs is a key factor in profit of the sheep breeding. mortality rate of lambs (or lamb mortality rate) in different breeds of sheep under different climatic conditions is varying from 15% to 50% and an average of 9% to 20% has been reported. survival rate is a combination trait that i...

walking being the oldest form of urban transport, and until the advent of major transformationsin transport technology in the nineteenth century, most cities were structured in ways that supported walkability.today, there is a change in transportation which emphasizes, the traditional pedestrian paths which are increasinglybecoming non-regulated spaces when compared to the urban spaces for auto...

genetic parameters were estimated for somatic cell score (scs) in dairy cattle of iran using test day records. the records of first lactation were extracted from the database of national animal breeding center for cows calved between 2001 and 2010. data included 222923 test-day records, obtained from 29668 animals distributed in 100 different herds. estimates were carried out through gibbs samp...

to estimate heritability and genetic trend for 305-d milk production and lactation persistency, a total of 130,668 monthly test day milk yields belonging to 15,183 first lactation holstein cows in 131 herds and calved from 2000 to 2009 were used. to calculate 305-d milk yield as well as lactation persistency, estimated parameters of wilmink’s exponential function were applied. the parameters of...

charcot-marie-tooth (cmt) is the commonest neurogenetic disorder with phenotypic and genotyping heterogeneity. cmt1a encompasses approximately 60% of all types of cmt and has ad inheritance. cmt1a maps to chromosome17 p11.2 and is majorly caused by 1.5 mb dna duplication that includes the peripheral protein 22 (pmp) genes. the severity, onset and progression of cmt1a vary markedly within and be...