نتایج جستجو برای: photodamage

تعداد نتایج: 802  

Journal: :Biochimica et Biophysica Acta (BBA) - Bioenergetics 2012

Journal: :Chemical communications 2015
Xiaomin Liu Hung-Cheng Chen Xianggui Kong Youlin Zhang Langping Tu Yulei Chang Fei Wu Tongtong Wang Joost N H Reek Albert M Brouwer Hong Zhang

We provide the first demonstration of a near infrared light driven water oxidation reaction in a molecule-based artificial photosynthetic device using an upconversion nano-photosensitizer. One very attractive advantage of this system is that using NIR light irradiation does not cause significant photodamage, a serious problem in molecular based artificial photosynthesis under visible light irra...

Journal: :Annals of the New York Academy of Sciences 1980

Journal: :Investigative Opthalmology & Visual Science 2011

Journal: :International journal of oncology 2008
Jitsuo Usuda Takeshi Hirata Shuji Ichinose Taichirou Ishizumi Tatsuya Inoue Keishi Ohtani Sachio Maehara Masae Yamada Hidemitsu Tsutsui Tetsuya Okunaka Harubumi Kato Norihiko Ikeda

It is very important to elucidate the mechanism of action and identify the molecular determinant of photodynamic medicine, in order to increase the number of clinical applications of photodynamic therapy (PDT) and perform personalized medicine. We have previously reported that PDT using some photosensitizers, such as phthalocyanine 4 (Pc 4) damages the anti-apoptotic protein Bcl-2, and that Bcl...

Journal: :Carcinogenesis 2012
Srirupa Roy Gagan Deep Chapla Agarwal Rajesh Agarwal

Better preventive strategies are required to reduce ultraviolet (UV)-caused photodamage, the primary etiological factor for non-melanoma skin cancer (NMSC). Accordingly, here we examined the preventive efficacy of silibinin against UVB-induced photodamage using mouse epidermal JB6 cells and SKH1 hairless mouse epidermis. In JB6 cells, silibinin pretreatment protected against apoptosis and accel...

Journal: :The Journal of pharmacology and experimental therapeutics 2005
Georg T Wondrak Myron K Jacobson Elaine L Jacobson

Photooxidative stress is a key mechanism in UVA-induced skin photodamage. Photoexcited states of endogenous UVA chromophores such as porphyrins, melanin precursors, and cross-link-fluorophores of skin collagen exert skin photodamage by direct reaction with substrate molecules (type I photosensitization) or molecular oxygen (type II), leading to formation of reactive oxygen species. Based on our...

Journal: :Indian Journal of Dermatology, Venereology, and Leprology 2012

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