This article addresses the effort made in the Pragmatic Case Study (PCS) method to enhance the quality and rigor of knowledge gained from psychoanalytic single case studies. Five limitations of typical psychoanalytic case or vignette presentations are reviewed and the ways in which the PCS method attempts to improve upon them are highlighted. The limitations include: (1) reliance on the therapi...

The striatum is a key brain structure involved in the processing of cognitive flexibility, which results from the balance between the flexibility demanded for novel learning of motor actions and the inflexibility required to preserve previously learned actions. In particular, the dorsolateral portion of the striatum (DLS) is engaged in the learning of action sequence. This process is temporally...

We show that the dynamics of large fractal colloid aggregates are well described by a combination of translational and rotational diffusion and internal elastic fluctuations, allowing both the aggregate size and internal elasticity to be determined by dynamic light scattering. The comparison of results obtained in microgravity and on Earth demonstrates that cluster growth is limited by gravity-...

Bilateral drug price and quantity indexes, based on comprehensive data for seven countries (US, Canada, France, Germany, Italy, Japan and the UK), refute the conventional wisdom that US drug prices are much higher than elsewhere, for Laspeyres (US-weighted) indexes. Previous drug-price comparisons are biased by unrepresentative samples and unweighted indexes. Quasi-hedonic regression shows that...

Homodyne photon correlation spectroscopy is used to measure the velocity difference delta v (l) over varying distance l. Different length scales are probed when the magnification factor M and the width S of a slit in the collecting optics are varied. The measured intensity autocorrelation function is found to be of scaling form for different values of M, provided S is kept at a value below the ...

We show that gelation of weakly attractive colloids is remarkably similar to the colloidal glass transition. Like the glass transition, dynamic light scattering functions near gelation scale with scattering vector, and exhibits a two-step decay with a power-law divergence of the final decay time. Like the glass transition, static light scattering does not change upon gelation. These results sug...

1 Middle East Technical University Department of Mechanical Engineering, Turkey [email protected] 2 Middle East Technical University Department of Electrical and Electronics Engineering, Turkey [email protected] 3 Middle East Technical University Department of Electrical and Electronics Engineering, Turkey [email protected] 4 Middle East Technical University Department of Electrica...

Few methods exist that can accurately handle dynamic light scattering in the regime between single and highly multiple scattering. We demonstrate dynamic light scattering Monte Carlo (DLS-MC), a numerical method by which the electric field autocorrelation function may be calculated for arbitrary geometries if the optical properties and particle motion are known or assumed. DLS-MC requires no as...

The ionic gelation process for the synthesis of chitosan nanoparticles was carried out in microdroplet reactions. The synthesis could be stopped instantaneously at different time points by fast dilution of the reaction mixture with DI water. Using this simple technique, the effect of temperature and reactant concentrations on the size and distribution of the nanoparticles formed, as a function ...

Understanding factors that structure regional biodiversity is important for linking ecological and biogeographic processes. Our objective was to explore regional patterns in riverine benthic invertebrate assemblages in relation to their broad positioning along the river network and examine differences in composition, biodiversity (alpha and beta diversity), and environmental drivers. We up-scal...