The whole plant of P. niruri was dried under shade and then macerated. 500 g of P. niruri was soaked in 3 litres of absolute a lcohol (Depar tment o f pharmacology , Manipa l ) . Af te r 24 hours , ex t rac t ion was star ted by ref lux condensat ion. The extract was concen t ra ted by d i s t i l l a t ion and then evaporated to dryness on a waterbath. 500 g of dr ied P. n i rur i y ie lded 85...

The present study was aimed at investigating the ameliorative effect of Emblica (Phyllanthus Emblica L) fruit extract (EFE) against alcohol-induced oxidative changes in plasma biochemical profile in rats. Alcohol administration (5 g/kg body wt/day) for 60 days resulted in significantly (P<0.05) higher levels of plasma nitrite/nitrate (NOx), total bilirubin, creatinine, and abnormalities in lipi...

This study aimed to evaluate the effects of aqueous extracts of dried Phyllanthus niruri L. (stonebreaker) leaves on Allium cepa L. root meristem cells at four concentrations, 0.02 (usual concentration), 0.04, 0.06 and 0.08mg/mL and exposure times of 24 and 48 hours. For each concentration we used a group of five onion bulbs that were first embedded in distilled water and then transferred to th...

BACKGROUND Phyllanthus amarus (Schum & Thonn), a plant belonging to the family of Euphorbiaceae is used in Ivorian traditional medicine to treat cardiovascular disorders such as hypertension. However, although this plant has been described as a diuretic agent, the underlying mechanism remains unclear. Therefore, the aim of the present study was to investigate the mechanism action of diuretic ef...

The majority of tribe Phyllantheae (Phyllanthaceae) is currently placed in the paraphyletic genus Phyllanthus and discussions have persisted on how to resolve this issue. Here, we split into ten monophyletic genera, which are all reinstatements former but with changes made circumscription constituent species each group. genera Breynia, Glochidion Synostemon were recently found be nested within ...

Phyllanthus emblica (PE) is a plant widely found in Indonesia, especially Sumatra island, and India. This study followed the OECD No. 420. The groups were divided based on gender, male female rats. Male rats into 6 groups, which male/female control, 2000 mg/kgBW, 5000 mg/kgBW. revealed that ethanol extract of (EEPE) doses mg/kgBW did not cause histological changes heart, liver, testes, ovaries,...

Medicinally important five Phyllanthus species viz. P. acidus (L.) Skeels, emblica L. (small fruit form), (large niruri L., reticulatus Poir. and urinaria were cytogenetically studied through orcein-staining for authentic characterization. This genus showed variation in somatic chromosome numbers such as 2n=2x=26 (x=13) acidus, reticulatus, 2n=6x=48 (x=8) 2n=10x=100 (x=10) (both small large for...