Physical inactivity-gene interactions result in changes in gene expression, leading to phenotypic changes in the skeletal muscle cell. A subpopulation of those genes that show changes in expression during physical inactivity are candidates for the environment-gene interactions that cross a threshold of biological significance such that overt clinical disease occurs. AMP kinase, GLUT4 and myosin...

OBJECTIVE We investigated the independent association between several neighbourhood built environment features and physical inactivity within a national sample of Canadian youth, and estimated the proportion of inactivity within the population that was attributable to these built environment features. METHODS This was a cross-sectional study of 6626 youth aged 11-15 years from 272 schools acr...

The COVID-19 disease caused by the SARS-CoV-2 virus, which started in Wuhan, capital of China's Hubei province, was declared a global epidemic World Health Organization. Restrictive measures based on physical (social) distance are taken to prevent spread disease, manifests itself with symptoms such as high fever, dry cough, shortness breath, weakness, and diarrhea. According settlement rules, n...

The classic modifiable risk factors for the development of coronary heart disease (CHD), derived from the Framingham Heart Study and other long-term epidemiological studies, are increased blood pressure, elevated plasma cholesterol, and cigarette smoking. However, evidence has been accumulating for many years suggesting that physical inactivity or the lack of exercise is also a potent force in ...

OBJECTIVES To estimate the prevalence of leisure-time physical inactivity (LTPI) and associated factors among healthcare workers. MATERIAL AND METHODS The cross-sectional study carried out with 2684 healthcare workers from 4 municipalities from the northeast region, Brazil. The LTPI was assessed by dichotomous question. The association between LTPI and the various independent variables was ex...