background: hb a2 is elevated in subjects with beta thalassemia minor but small percent of carriers have normal hb a2 with elevated levels of hbf (2-10%). this type of thalassemia is called delta beta thalassemia, and can be missed in pre-marriage hematologic consults or screening which leads to increased risk of child birth with beta thalassemia major. materials and methods: in this prospectiv...

background: children affected with sickle cell disease (scd) are at increased risk for severe morbidity and mortality, especially during the first 3-5 years of life. it is suggested that early treatment can improve the condition. the aim of this pilot study was to estimate the incidence of hemoglobin s (hbs) by umbilical cord blood screening in khorramshahr and abadan cities in southwest of ira...

background: the aim of this perspective study was to assess the frequency of hemoglobinopathy mutational genes among voluntary hemoglobinopathy carrier couples-to-be referred to thalassemia center, shafa hospital, affiliated to ahvaz jondidishapur university of medical sciences (ajuoms), during their first trimester of pregnancy for genetic screening and counseling for prenatal diagnosis (pnd)....

introduction: congenital hypothyroidism is one of the most preventable causes of mental retardation. worldwide, incidences vary from 1:3000 to 1:4000 and mean incidence in iran is estimated to be 1:1000. neonatal screening and early treatment within first 2 weeks of neonatal period can prevent neurocognitive deficits. we aimed to study the incidence of ch and increased levels of tsh in yazd pro...

background: celiac disease (cd) may be misdiagnosed as irritable bowel syndrome (ibs) resulting in long delays in diagnosing cd. there are contradictory reports on the association of cd with ibs.appropriateness of screening all patients with ibs for cd and how to screen them are still under question. materials and methods: in a cross-sectional study, 328 ibs patients (rome ii) referred to the p...

objectives: there are various developmental screening tools that are different in terms of psychometric characteristics and choosing the best one is challenging for the pediatrician. this research was designed to identify the validity and reliability of parents evaluation of developmental status, a developmental screening questionnaire, in 4-60 months-old children in the city of tehran. methods...

purpose: uncorrected visual acuity is the only variable measured in vision screening programs in many countries worldwide. the aim of this study was to calculate the sensitivity, specificity, and predictive value of the uncorrected visual acuity in the screening programs for the diagnosis of refractive errors. methods: in this cross-sectional study, of 4,157 students in the first year of primar...

introduction: children learn to communicate by hearing sounds. if there is hearing loss, the cognitive and speaking abilities and language learning will deteriorate. early detection and intervention are important factors in the successful treatment of hearing loss in children. hearing loss (hl) is divided into two main groups: conductive hearing loss (chl) and sensorineural hearing loss (snhl),...

background tubercle bacilli most often are transmitted from one person by the airborne route. the aim of the present study was to determine the frequency of latent tuberculosis infection and active pulmonary tuberculosis among patients with chronic psychiatric disorders in hamedan. patients and methods in a cross sectional study, 215 patients with chronic psychiatric disorders were investigated...

background: to determine the sensitivity, specificity, positive predictive value (ppv), and negative predictive value (npv) of the national vision screening program for 7 yr old children in iran. methods: in this cross-sectional study, eight cities in iran were selected through multistage cluster sampling. selected cities were sari, birjand, ardabil, mashhad, bandar abbas, dezful, yazd, and ara...