Spices are a diverse group of wide variety dietary additives consumed all over the world. Study spices is good example to illustrate anyone complementarily science and tradition. A spice may be any dried part, an herb, pleasantly aromatic like seed, fruit, root, bark or flower plant, which commonly used for flavor, color, as preservative medicine. From ancient time have being playing major role...

Background: Oxidative stress is found as one of the causes in various pathological conditions. It has been proven in many studies that medicinal plants have antioxidant constituents that help in coping with the oxidative stress. Therefore, the present study aimed at evaluating the antioxidant effects of Nyctanthes arbor tristis leaves extract on the liver of Freund’s complete adjuvant (FCA) ind...

Gymnema sylvestre(G. sylvestre) (Asclepiadaceae) commonly known as ‘Gudmar’ in Hindi is an important medicinal plant (Climber) used in different systems of medicine as a remedy for the treatment of diabetes, rheumatism, cough, ulcer, jaundice, dyspepsia, constipation, eyes pain and also in snakebite. The major phytoconstituents of gymnema sylvestra are gymnemic acids, gudmarin and saponins[1]. ...

Antinociceptive and anti-inflammatory potentials of methanolic extract of Bridelia retusa fruit (BRME) were evaluated against different animal models in rodents. Antinociceptive effects of BRME were assessed in mice using the acetic acid-induced writhing and formalin test. Anti-inflammatory effects of BRME in three different doses, namely, 100, 200, and 400 mg/kg, were evaluated by utilizing di...

The aggressive nature of estrogen receptor (ER)-negative breast cancer subtype obligates for innovative targeted therapies. The present study aimed to investigate the phytoconstituents and specific anticancer activities of Rheum emodi rhizome, a known food source used locally to treat various ailments. Petroleum ether extracts (hot [PHR] and cold [PCR]) of R. emodi, exhibited significant free r...

Tinospora cordifolia (Thunb.) Miers, Menispermaceae, is a dioecious creeper, commonly known as "Giloe" or "Guduchi" with significant medicinal importance in the traditional systems of medicine. It is designated as Rasayana drug in Ayurveda and recommended for a number of diseases and also as adaptogen and immunomodulator. The safety and efficacy of herbal medicines are closely correlated with t...

Objective: The aim of this study was to investigate CYP1A interaction of crude extracts (ethanolic, methanolic, hydromethanolic & aqueous) of Withania somnifera and its principal phytoconstituents (withaferin-A and withanolide-A) in rat and human liver microsomes. Methods: In vitro study were carried out in both rat & human liver microsomes while, in vivo CYP1A interaction potential was investi...

To screen the wound healing activity of different extracts of Allium cepa L. in excision, incision and dead space wound models in albino rats. The tubers of Allium cepa L. (Family Liliaceae) were exhaustively defatted with petroleum ether (40-60C) and the marc was subjected to continuous extraction with solvent ether, chloroform, alcohol and chloroform water I.P. All the extracts were tested fo...

Depletion of acetylcholine in the central nervous system (CNS) is responsible for memory loss and cognition deficit. Enzyme acetylcholinesterase (AChE) is responsible for destruction of acetylcholine (Ach) in the brain. Many herbal plant extracts have been investigated for their potential use in the treatment of Alzheimer's disease (AD) by inhibiting AChE and upregulating the levels of Ach. The...

Plan: The aim of the present research was focused on cytotoxic, antiviral and antibacterial properties and the main phytoconstituents of Terminalia laxiflora leaf methanolic extract. Methodology: The methanolic 80% extract of Terminalia laxiflora leaves was tested for cytotoxicity evaluation in Vero cells in-vitro, anti-HSV-1 activity and antibacterial activity determinations against some bacte...