Oral administration of a methanolic extract of Piper nigrum leaf (PN-ext, 50, 200 and 500 mg/kg) showed a potent dose-dependent inhibition of dinitrofluorobenzene (DNFB)-induced cutaneous reaction at 1 h [immediate phase response (IPR)] after and 24 h [late phase response (LPR)] after DNFB challenge in mice which were passively sensitized with anti-dinitrophenyl (DNP) IgE antibody. Ear swelling...

In this paper, the antioxidant activities of black and white pepper (Piper nigrum L.) essential oils (BEO and WEO) were evaluated and compared based on radical scavenging activities, reducing power, and DNA oxidative damage protection assays. The results showed that EOS exhibited antioxidant activities, and DNA damage protective effect to various extents. For BEO and WEO, they showed a concentr...

Plants used in popular diet were studied for anti-Helicobacter pylori activity and their effect on the expression of interleukin-8 (IL-8) from H. pylori infected gastric epithelial cells. Extracts were prepared of Allium sativum (A. sativum), Cuminum cyminum (C. cyminum), Piper nigrum (P. nigrum) and their mix in two different dilutions. AGS cell line and H. pylori strains were used for co-cult...

Background: Pepper plants belong to the Piperaceae family with many pharmacological activities. The fruits of these have been widely used traditionally for various therapies, one which is an aphrodisiac. Objective: purpose this study was determine aphrodisiac activity three pepper plants, Piper nigrum, retrofractum, and cubeba prove their traditional use. Methods: level piperin, active compound...

Background: In recent years, drug resistance to human pathogenic fungi has been increased. Medicinal plants are one way to overcome antibiotic resistance. The aim of this study was to evaluate the antifungal and inhibitory activity of five medicinal plants on the growth of Candida albicans. Methods: This study was done in the Microbiology Lab of Shahid Bahonar University of Kerman, Iran in 2...

Fusarium disease causes considerable losses in the cultivation of Piper nigrum, the black pepper used in the culinary world. Brazil was the largest producer of black pepper, but in recent years has lost this hegemony, with a significant reduction in its production, due to the ravages produced by the Fusarium solani f. sp. piperis, the fungus which causes this disease. Scientific research seeks ...