The last decade has seen a surge in the treatment options for metastatic renal cell carcinoma and life expectancies are now approaching 3 years from diagnosis. There is some suggestion that, for now at least, we may have reached a plateau in efficacy. Patients are often stable and on treatment for years rather than months. Attention has therefore shifted to a focus on patient preference rather ...

We present near–infrared, H–band (1.65μm), surface photometry of 174 spiral galaxies in the area of the Pisces–Perseus supercluster. The images, acquired with the ARNICA camera mounted on various telescopes, are used to derive radial profiles of surface brightness, ellipticities, and position angles, together with global parameters such as H-band magnitudes and diameters . The mean relation bet...

Unlike the substantial coherent bulk motion in which our local patch of the Cosmos is participating, the amplitude of the random motions around this large scale flow seems to be surprisingly low. Attempts to invoke global explanations to account for this coldness of the local cosmic velocity field have not yet been succesfull. Here we propose a different view on this cosmic dilemma, stressing t...

Background Late Gadolinium Enhancement (LGE) allows imaging of infarction by visualizing the accumulation of contrast agent within the myocardium using an inversion recovery (IR) prepared sequence. However, myocardial hyperenhancement can sometimes be poorly detected in the vicinity of epicardial fat because both fat and hyperenhanced tissue appear bright. Thus, a method for fat signal suppress...

The present paper aims to study the occurrence of monogenean species infecting gills wild Hemichromis elongatus (Pisces). Fish specimens were caught with nets, fixed in 10% formalin and then dissected. Monogenean found removed under a stereomicroscope needle, mounted between slide cover slip drop hematoxylin eosin. Among five parasite found, only O. voltaensis C. euzeti infesting their host alo...

INTRODUCTION The state of understanding of the destructive SEGR event in power MOSFETS is relatively mature with large published efRorts, both experimental [1-5] and theoretical [6-8]. However, gaps remain in the understanding of the phenomenon, including unexplained experimental anomalies, empirical-only dependencies on some important device and incident ion physical parameters, and limited in...

An Internet server at http://bip.weizmann.ac.il/dipol calculates the net charge, dipole moment and mean radius of any 3D protein structure or its constituent peptide chains, and displays the dipole vector superimposed on a ribbon backbone of the protein. The server can also display the angle between the dipole and a selected list of amino acid residues in the protein. When the net charges and d...