Cell migration and spreading involve the coordination of membrane trafficking, actomyosin contraction, and modifications to plasma membrane tension and area. The biochemical or biophysical basis for this coordination is however unknown. In this study, we show that during cell spreading, lamellipodia protrusion flattens plasma membrane folds and blebs and, once the plasma membrane area is deplet...

semen hyperviscosity (shv) is one of the factors involved in deficiency in sperm function. this research aimed to evaluate seminal plasma total antioxidant capacity (tac) and malondialdehyde (mda) levels in infertile patients with hyperviscous and non-hyperviscous semen samples to understand whether hyperviscous semen is associated with oxidative damage in infertile subjects. in this cross sect...

background: recent results have provided increasing evidence to support involvement of membrane damage in the mechanism of ionizing radiation induced killing of mammalian cells. these findings have stimulated renewed interest in evaluating the damage to membrane as a primary initiator in radiation-induced cell killing especially in apoptotic death. the present study was aimed to gain deeper ins...

Introduction The membrane-associated form of heat shock protein 70 (Hsp70) represents a promising target for fluorescence-based intraoperative molecular imaging. Contrary to normal tissue cells, Hsp70 is selectively upregulated on the plasma membrane many tumor entities, including HNSCC.We investigated whether topical application fluorescence-labeled peptide tracer (TPP-IRDye800), that specific...

The chemical composition of plasma membrane fractions isolated from orchard grass seedlings (Dactylis glomerata L.) was analyzed and compared with endomembranes. The plasma membrane is characterized by an enrichment of sterols and a lower degree of unsaturation of phospholipids. Steryl glycosides were found to be one of the lipid components of the plasma membrane, but steryl esters and galactol...

Poly(vinyl alcohol) (PVA)/polyethersulfone (PES) composite membranes were fabricated using two PVA polymers with molecular weights of 50,000 and 15,000 different crosslinker agents. The membrane the top layer consisting formaldehyde as found to have a better separation factor than others for pervaporative dehydration isopropanol. While adding 1.0 wt% graphene oxide could represent pervaporation...