multiple myeloma (mm) is characterized by progressive proliferation of malignant plasma cells, usually initiating in the bone marrow. mm can affect any organ; a total of 7 - 18% of patients with mm demonstrate extramedullary involvement at diagnosis. non-secretory multiple myeloma (nsmm) is a rare variant that accounts for 1 - 5% of all cases of multiple myeloma. the disease is characterized by...

extramedullary plasmacytoma (emp) is a rare neoplasm of soft tissue which usually arises in the respiratory tract, nasal cavity, sinuses and nasopharynx. multiple extramedullary plasmacytomas are extremely rare, especially those that are not associated with multiple myeloma.we describe multiple primary emp in a 37 year old man, without involvement of bone or bone marrow. emp usually has a good ...