OBJECTIVE Platelets and inflammatory cells are vital elements of acute coronary syndromes (ACS). Recent studies have shown that the platelet-to-lymphocyte ratio (PLR) is associated with several malignancies; however, there are not enough data in cardiovascular diseases. Therefore, the aim of this study was to explore the association between PLR and in-hospital mortality in patients with ACS. ...

BACKGROUND The platelet-lymphocyte ratio (PLR) and neutrophil-lymphocyte ratio (NLR) have been reported as prognostic factors in various cancers, but their roles in metastatic renal cell cancer (mRCC) remain unclear. We investigated the significance of PLR and NLR, along with that of established prognostic factors, in mRCC patients receiving first-line tyrosine kinase inhibitors (TKI). METHOD...

OBJECTIVE To test the hypothesis that passive leg raising (PLR) induces changes in arterial pulse pressure that can help to predict the response to rapid fluid loading (RFL) in patients with acute circulatory failure who are receiving mechanical ventilation. DESIGN Prospective clinical study. SETTING Two medical ICUs in university hospitals. PATIENTS Thirty-nine patients with acute circul...

BACKGROUND Systemic inflammatory parameters, such as the elevator PLR (platelet-lymphocyte ratio), the NLR (neutrophil-lymphocyte ratio) and the platelet count (PLT), have been found to be associated with the prognosis in gastric cancer; however, these results, especially those relating to the PLR, remain inconsistent. So we aimed to evaluate the prognostic role of the PLR in gastric cancer by ...

The prognostic value of platelet to lymphocyte ratio (PLR) in hepatocellular carcinoma (HCC) is controversial. Thus, a meta-analysis was carried out to evaluate the correlation between PLR and outcomes as well as clinical characteristics in HCC. Studies were identified through searching PubMed, Embase, and Web of Science. The combined hazard ratio (HR) with 95% confidence interval (CI) was comp...

Objectives In this study, we aimed to demonstrate the relationship between he neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte (PLR), neutrophil/monocyte rate (NMR) and mean platelet volume (MPV) in patients with BIRADS grades of benign breast lesions. Background many recent studies, NLR, PLR, NMR MPV change significantly connection chronic inflammation are suggested for use as prognostic...

Atypical pupillary light reflexes (PLR) has been observed in children with autism spectrum disorders (ASD), which suggests potential autonomic nervous system (ANS) dysfunction in ASD. ANS is also involved in modulating sensory processing and sensory dysfunction has been widely reported in children with ASD. However, the potential association between physiological measurements of PLR and behavio...

BACKGROUND Markers of preoperative tumor immunity, such as platelet-to-lymphocyte ratio (PLR), have been reported to be prognostic factors for patients with various cancers. However, the relationship between PLR and the prognosis of non-small cell lung cancer (NSCLC) patients treated with surgery and adjuvant chemotherapy as a multidisciplinary treatment is unknown. METHODS We enrolled 327 NS...

BACKGROUND Bell's palsy is the most frequent cause of unilateral facial paralysis. Inflammation is thought to play an important role in the pathogenesis of Bell's palsy. AIMS Neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) are simple and inexpensive tests which are indicative of inflammation and can be calculated by all physicians. The aim of this study was to reve...

Intrinsically photosensitive retinal ganglion cells (ipRGCs), whose photopigment melanopsin has a peak of sensitivity in the short wavelength range of the spectrum, constitute a common light input pathway to the olivary pretectal nucleus (OPN), the pupillary light reflex (PLR) regulatory centre, and to the suprachiasmatic nuclei (SCN), the major pacemaker of the circadian system. Thus, evaluati...