A comprehensive comparison of positive matrix factorization (PMF) and molecular marker-based chemical mass balance (CMB-MM) modeling on PM2.5 source contributions was conducted for particulate matter measurements taken at Jefferson Street, Atlanta, Georgia (JST). The datasets used in each type of receptor modeling were different: CMB-MM used data of primarily organic tracers plus a couple eleme...

Several international working groups cooperated to propose new diagnostic guidelines for polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF) to the steering committee of the World Health Organization. Because JAK2 mutation status presents a decisive diagnostic test in PV, this feature was introduced as a major criterion. Minor criteria, such as characteristic...

Using plastic mulching for farmland is booming around the world. Despite its benefit of protecting crops from unfavorable conditions and increasing crop yield, the massive use of the plastic-mulching technique causes many environmental problems. Therefore, timely and effective mapping of plastic-mulched farmland (PMF) is of great interest to policy-makers to leverage the trade-off between econo...

Anemia is a cardinal manifestation of primary myelofibrosis (PMF) and constitutes a negative prognostic factor, being an independent risk factor for survival both in the international prognostic score system (IPSS) and dynamic IPSS (DIPSS)-plus. Anemia in myelofibrosis is also inversely correlated with patient-reported quality of life. Between 35 and 54% of patients with PMF are anemic at diagn...

BACKGROUND Perimitral flutter (PMF) is a common form of left atrial tachycardia after atrial fibrillation (AF) ablation. The mitral isthmus (MI) is the standard ablation target. However, in some cases bidirectional block cannot be achieved. OBJECTIVE The purpose of this study was to describe the first experience using a transthoracic epicardial (TTE) approach to treat recurrent PMF after prio...

PMF. Although the number of patients was small, one of rimary myelofibrosis (PMF) is a clonal hematopoietic disorder haracterized by an initial prefibrotic proliferative phase that ver time progresses to bone marrow fibrosis, extramedullary ematopoiesis, peripheral blood cytopenias and an increased isk of developing acute myeloid leukemia (AML). In recent ears, the molecular mechanisms that cau...

Primary myelofibrosis (PMF) is a Philadelphia-negative (Ph-) myeloproliferative disorder, showing abnormal CD34+ progenitor cell trafficking, splenomegaly, marrow fibrosis leading to extensive extramedullary haematopoiesis, and abnormal neoangiogenesis in either the bone marrow or the spleen. Monocytes expressing the angiopoietin-2 receptor (Tie2) have been shown to support abnormal angiogenic ...

We investigated the lipid-lowering effects of methanolic extract of Vernonia amygdalina (VA) leaves in rats fed an high cholesterol diet, and compared with a standard hypolipidemic drug, Questran (Qu). The effects of VA on the lipid profile were assessed by measuring the levels of total cholesterol, triglyceride, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) choleste...

Primary myelofibrosis (PMF) is a chronic Philadelphia-negative myeloproliferative neoplasm characterized by hematopoietic stem cell-derived clonal myeloproliferation, involving especially the megakaryocyte lineage. To better characterize how the altered expression of microRNAs might contribute to PMF pathogenesis, we have previously performed the integrative analysis of gene and microRNA expres...