BACKGROUND Commensal Escherichia coli are a prominent reservoir of genes coding for antibiotic resistance and also responsible for endogenous infections in pregnant women. We studied the factors in pregnant women associated with carriage of multi-drug resistant (MDR) E. coli and genetic determinants of antibiotic resistance in them. METHODS Women attending to Obstetric and Gynaecology departm...

OBJECTIVE The aim of this study was to explore the occurrence and molecular characterization of extended-spectrum β-lactamases (ESBL), plasmid-mediated AmpC β-lactamase (pAmpC) and carbapenemases among ESBL-producing multidrug resistant (MDR) Escherichia coli from dogs and cats in the United States. METHODS Of 2443 E.coli isolated from dogs and cats collected between August 2009 and January 2...

Background: Quinolone resistant Salmonella serotypes have been reported in recent years and become increasingly widespread worldwide. Objectives: We evaluated the molecular mechanism of quinolone resistance non-typhoidal strains isolated from clinical samples Tehran, Iran. Methods: The present study included isolates originated hospitalized individuals outpatients Serotyping nalidixic acid-resi...

Resistance to quinolones in Gram-negative bacteria is usually mediated by the following: (i) chromosomal mutations that alter the target enzymes, DNA gyrase and topoisomerase IV, in their quinolone resistance-determining regions (QRDR), (ii) changes in drug entry (loss of porin channels), and (iii) the presence of plasmid-mediated quinolone resistance (PMQR) determinants [qnrA, qnrB, qnrS, qnrC...

In Uruguay, the mortality of dairy calves due to infectious diseases is high. Escherichia coli a natural inhabitant intestinal microbiota, but can cause several infections. The aim work was characterize E. isolates from and extraintestinal origin dead newborn calves. Using PCR, virulence gene characteristics pathogenic were searched. molecularly characterized phylogroup, serogroup Stx subtype d...

The objective of this study was to identify mutations in the Quinolone Resistance Determining sources Regions (QRDR) of the gyrA, gyrB, parC, and parE genes and to determine if any of the qnr variants or the aac(6')-Ib-cr variant were present in strains of Salmonella spp. isolated in Brazil. A total of 126 Salmonella spp. strains from epidemic (n = 114) and poultry (n = 12) origin were evaluate...