This thesis considers problems in two areas in the healthcare operations: Kidney Paired Donation (KPD) and scheduling medical residents in hospitals. In both areas, we explore the implications of policy change through high fidelity simulations. We then build stochastic models to provide strategic insight into how policy decisions affect the operations of these healthcare systems. KPD programs e...

ing logical rules should be justified and based on the data that we can observe from a real system. In other words, if a logical rule is abstracted, the input data for the abstracted logical rule should be observable in the real system, and its output data also should be comparable to the observable results of the real system. An abstracted model does not provide more I/O data than the original...

W E are extremely pleased to present this special issue of the IEEE TRANSACTIONS ON SYSTEMS, MAN, AND CYBERNETICS, PART B. The importance of adaptive dynamic programming (ADP) to feedback control engineers is that it affords a methodology for learning optimal control actions online in real time based on system performance without necessarily knowing the system dynamics. When such knowledge is r...

In this paper, a novel multi-fidelity modelling-based optimisation framework is developed for the robust design of composite structures. The proposed provides significant savings on computation time compared to both conventional and high-fidelity modelling methods while maintaining an acceptable level accuracy. Artificial neural networks (ANNs) multi-level approach are incorporated into formula...

Multifidelity Monte Carlo (MFMC) estimation combines lowand high-fidelity models to speedup the estimation of statistics of the high-fidelity model outputs. MFMC optimally samples the lowand high-fidelity models such that the MFMC estimator has minimal mean-squared error for a given computational budget. In the setup of MFMC, the low-fidelity models are static, i.e., they are given and fixed an...

BACKGROUND Implementation fidelity is critical to the internal and external validity of implementation research. Much of what is written about implementation fidelity addresses fidelity of evidence-informed interventions rather than fidelity of implementation strategies. The documentation and reporting of fidelity to implementation strategies requires attention. Therefore, in this scoping revie...

We derive several bounds on fidelity between quantum states. In particular we show that fidelity is bounded from above by a simple to compute quantity we call super–fidelity. It is analogous to another quantity called sub–fidelity. For any two states of a two– dimensional quantum system (N = 2) all three quantities coincide. We demonstrate that sub– and super–fidelity are concave functions. We ...

In many situations across computational science and engineering, multiple computational models are available that describe a system of interest. These different models have varying evaluation costs and varying fidelities. Typically, a computationally expensive high-fidelity model describes the system with the accuracy required by the current application at hand, while lower-fidelity models are ...