-To obtain more insight in the ring-opening polymerization of lactones, complex formation of the initiators tetraphenyltin, stannous octoate, tin tetrachloride, aluminium bromide and triisobutylaluminium (TIBA), and the monomers L(-)-lactide, D,e-lactide and glycolide was studied by i.r.-spectroscopy. When equimolar benzene or toluene solutions of initiators and monomers were combined, only com...

Although it has been repeatedly indicated the importance to develop implantable devices and cell culture substrates with tissue-specific rigidity, current commercially available products, in particular substrates, have rigidity values well above most tissues body. Herein, six resorbable polyester films were fabricated using compression moulding a thermal presser into tailored stiffness by appro...

Biodegradable micelle systems with both extracellular stabilities and specific targeting properties are highly desirable for anti-cancer drug delivery. Here, we report a biodegradable and crosslinkable poly(propylene fumarate)-co-poly(lactide-co-glycolide)-co-poly(ethylene glycol) (PPF-PLGA-PEG) copolymer conjugated with folate (FA) molecules for receptor-mediated delivery of doxorubicin. Micel...

Glycolide and lactide function as the commonly used diester monomers for preparation of high-molecular weight, degradation-prone (co-)polyesters. Both glycolide lactide-based polymers are widely in medicine, pharmaceuticals, food industry, additive technologies. This review on diesters, spanning research from 1833-1854 to present, encompassing their structural peculiarities, physico-chemical pr...