Self-diffusion in polymer solutions studied with pulsed-field gradient nuclear magnetic resonance (PFG NMR) is typically based either on a single self-diffusion coefficient, or a log-normal distribution of self-diffusion coefficients, or in some cases mixtures of these. Experimental data on polyethylene glycol (PEG) solutions and simulations were used to compare a model based on a gamma distrib...

Human papillomavirus (HPV) cause common warts, laryngeal papilloma and genital condylomata and might lead to development of cervical cancer. Lactoferrin (LF) is a member of the transferrin family, which has antiviral activity against HPV-16. LF is an important player in the defense against pathogenic microorganisms and has also been shown to have activity against several viruses including herpe...

BACKGROUND AND AIMS The main aims of the present study were to formulate an anti-age cream based on vegetal ingredients and ferulic acid and to evaluate the physical characteristics and the efficacy of the cream. METHODS The active ingredients were Centella asiatica oil, Spilanthes acmella oil, Zingiber officinale extract and ferulic acid. Formulation 1 (F1) was prepared using glyceryl steara...

BACKGROUND Preparation of nanoformulations using natural products as bioactive substances is considered very promising for innovative larvicidal agents. On this context, oil in water nanoemulsions develop a main role, since they satisfactorily disperse poor-water soluble substances, such as herbal oils, in aqueous media. Pterodon emarginatus, popularly known as sucupira, has a promising bioacti...

Background:  Nanostructured lipid carriers (NLCs) of sumatriptan succinate (SS) were prepared by using lavender oil.  In ancient days, lavender oil was used for the treatment of a migraine. The natural anti-migraine agent, lavender oil, combined with an anti-migraine drug such as SS in a nano-formulation, will be a practical alternative approach in migraine therapy.  Objective: NLCs of sumatri...

this paper discusses about preparation of biodegradable polymer /clay nanocomposites based on organically modified montmorillonite clay; i.e. cloisite 10a and biodegradable polymer chitosan by solution mixing technique and their characterization. the nanocomposites were successfully prepared and their structures were characterized by powder x-ray diffraction (xrd), particle size analyzer (beckm...

In pharmaceutical view, nanoemulsion is one of the major dosage forms in delivering active ingredients to the target area which has attracted considerable attention in recent years for its application in personal care and cosmetic products also due to their ability to improve the penetration and permeation of active ingredients through the skin. The aim of this study was to formulate nanoemulsi...

OBJECTIVES Spray-dried formulations offer an attractive delivery system for administration of drug encapsulated into liposomes to the lung, but can suffer from low encapsulation efficiency and poor aerodynamic properties. In this paper the effect of the concentration of the anti-adherent l-leucine was investigated in tandem with the protectants sucrose and trehalose. METHODS Two manufacturing...