© Springer International Publishing Switzerland 2015 F. Puoci (ed.), Advanced Polymers in Medicine, DOI 10.1007/978-3-319-12478-0_9 Abstract Polymers represent the foundation of modern restorative Dentistry. The majority of dental procedures currently utilized in clinical dentistry depend on the close interaction of polymeric materials with dental tissues. In fact, the dental matrix itself is l...

A systematic, comprehensive strategy that optimizes sample preparation and chromatography to minimize matrix effects in bioanalytical LC/MS/MS assays was developed. Comparisons were made among several sample preparation methods, including protein precipitation (PPT), liquid-liquid extraction (LLE), pure cation exchange solid-phase extraction (SPE), reversed-phase SPE and mixed-mode SPE. The inf...

Biofilms are defined as bacterial communities surrounded by a structured extracellular polymeric matrix which is adhered to biotic or abiotic surfaces [1]. Biofilm formation develops in two steps: firstly, a primary attachment occurs onto polymeric surfaces, mediated partly by cell-wall associated adhesins; secondly, cell-cell proliferation forms a multilayered biofilm, mediated by production o...

Microspheres have been prepared from the resorbable linear polyester of beta-hydroxybutyric acid (polyhydroxybutyrate, PHB) by the solvent evaporation technique and investigated in vitro and in vivo. Biocompatibility of the microspheres has been proved in tests in the culture of mouse fibroblast cell line NIH 3T3 and in experiments on intramuscular implantation of the microspheres to Wistar rat...

Gelatin, chitosan and hyaluronic acid are natural components used to prepare polymeric scaffold in tissue engineering. The physical properties of these materials confer an appropriate microenvironment for cells, which can be used as a regeneration system for skin and cartilage. In this work, we prepared and characterized a Gelatin/Chitosan/Hyaluronan lyophilized-polymer. Physical properties of ...

Epoxy and dicyclopentadien (DCPD) are two common healing agents, which are introduced into epoxy matrix through encapsulation in order to prepare self-healing composites. In a comparative study, the compatibility of healing agents and epoxy matrix is investigated through experimental tests and DFT calculations. The interaction energy is considered to be the determinative parameter in DFT calcul...

Virtually all cells living in multicellular structures such as tissues and organs are encased in an extracellular matrix. One of the most important features of a biofilm is the extracellular polymeric substance that functions as a matrix, holding bacterial cells together. Yet very little is known about how the matrix forms or how matrix components encase bacteria during biofilm development. Pse...

Recently micro particles or microspheres have gained great attention due to their free flowing powder characteristics and biodegradable nature generally made up of protiens or synthetic polymeric materials having particle size in the range of 1-200μm. Depending upon the encapsulation of active drug moieties there are two types of microspheres (microcapsules and micro matrices). Microcapsules ar...

The challenge to synthesize and characterise novel materials exhibiting outstanding properties requires the involvement of interdisciplinary groups with complementary expertise. This is the case of polymeric films and gels with incorporated magnetic components. Particularly, PVC composite matrix where magnetic nanoparticles are embedded represents one of the most attractive and emerging type of...

Macromolecular or polymeric liquids consist of polymer solutions, polymer melts, particle suspension fluids, and many biological fluids. Polymer solutions are made of polymers dissolved in solutions or solvent; polymer melts are molten polymers; particle suspension fluids consist of solid particles suspended in a matrix fluid which may be a viscous or viscoelastic fluid, blood flows consist of ...