Lung disorders induced by inhaled inorganic particles such as crystalline silica are characterized by chronic inflammation and pulmonary fibrosis. Here, we demonstrate the importance of type I interferon (IFN) in the development of crystalline silica-induced lung inflammation in mice, revealing that viruses and inorganic particles share similar signaling pathways. We found that instillation of ...

Polymorph selection in thin films of quinacridone obtained by the soluble latent pigment precursor method is found to be driven crystalline form a combined low-frequency Raman spectroscopy and X-ray diffraction study.

We present results of computer simulations of homogeneous crystal nucleation in the Gaussian core model. In our simulations, we study the competition between the body-centered-cubic (bcc), face-centered-cubic (fcc), and hexagonal-close-packed crystal phases. We find that the crystal nuclei that form from the metastable fluid phase are typically "mixed"; they do not consist of a single crystal p...

The quantities of two forms of crystalline silica, tridymite and cristobalite, in heated rice husk ash (RHA) samples were determined by X-ray diffraction (XRD) and chemical methods. Two RHA samples, containing 93% SiO2 and 2-3% K2O, were prepared from charcoaled rice husk products and heated to above 900 degrees C. The crystalline silica made up over 60-80% of the total silica in the heated RHA...

C293 physico-chemical properties. NN414 is a very weak acid with pKa = 8.5, log P = 1.6, and molar weight Mw = 291.8 g/mol. Two true polymorphs, A and B, of this compound have been identified. Polymorph A crystallizes in needleshaped crystals with a triclinic unit cell by precipitation from a variety of solvents such as acetic acid, acetonitrile, diluted ammonia, methanol, N-methyl-pyrrolidone,...

We created an exposure database of respirable crystalline silica levels in the construction industry from the literature. We extracted silica and dust exposure levels in publications reporting silica exposure levels or quantitative evaluations of control effectiveness published in or after 1990. The database contains 6118 records (2858 of respirable crystalline silica) extracted from 115 source...

Studies reporting the findings of exposure to crystalline silica dust during concrete finishing in construction settings are scarce due to the dynamic nature of the activity and the existence of many confounding factors. This study was initiated to explore the issue. A total of 49 personal respirable dust samples were collected during concrete finishing while workers used hand-held grinders. On...