Adenocarcinoma is relatively less common on the tongue.[1] Polymorphous low‐grade adenocarcinoma (PLGA) is a malignant tumor of minor salivary glands which is slow growing and carries a low metastatic potential. Histologically, PLGA exhibits a spectrum of growth patterns such as cribriform, tubular, trabecular, fascicular and solid structures. Concentric whorls forming target‐like patterns are ...

Polymorphous low-grade adenocarcinoma (PLGA) is a low-grade malignant infiltrative tumor of the minor salivary glands. According to data from PubMed (National Center for Biotechnology), one case of PLGA involving the left main bronchus and one case involving the right main and upper lobar bronchi have previously been reported. Here, we describe the first case of PLGA originating in the trachea ...

Background & Objective To evaluate usefulness of immunohistochemical marker C-kit (CD117) in differentiating Adenoid cystic carcinoma (AdCC) from Polymorphous low-grade adenocarcinoma (PLGA) in patients of salivary gland carcinomas. AdCC is a malignant salivary gland neoplasm with poor prognosis. PLGA is a salivary gland malignancy with indolent growth pattern. Differentiating between the two e...

Polymorphous low-grade adenocarcinoma (PLGA) is a malignant neoplasm of low aggressiveness that occurs almost exclusively in the minor salivary glands, primarily those in the palate. We report a case of PLGA that arose in the base of the tongue and subsequently metastasized to the neck. The tumor was resected through the oral cavity with wide margins and dissection. The neck metastasis was trea...

Abstract The polymorphous low-grade neuroepithelial tumor of young (PLNTY) is considered as one among the tumor; per WHO-2021 classification Brain Tumors in fifth edition. term PLNTY was first coined by Huse 2016. These morphologically variable tumors are characterized their oligodendroglioma-like cellular components, infiltrative growth pattern, and Cluster Differentiation 34 (CD34) immunoposi...

Necrobiotic xanthogranuloma This presents as multiple sharply demarcated, indurated, non-tender dermal or subcutaneous nodules and plaques. Periorbital involvement is common. Lesions vary from violaceous to red orange, and enlarge to form infiltrative plaques that may show central atrophy. Though most of the lesions are asymptomatic, some may be pruritic or painful. Ulceration and scarring are ...