Toxic water soluble polymeric 3-alkylpyridinium salts isolated from the sponge Raniera sarai strongly inhibited AChE in vitro. In vivo, experimental animals died due to plugs formed in microcirculation. The mechanism of this plug formation is unknown. In vitro, the toxin did not affect the coagulation rate, but the rate of platelet aggregation was accelerated in a dose-dependent manner. The hem...

Small-angle neutron scattering was used to probe the interfacial structure of nitrogen-in-water foams created using a series of tri-block polymeric surfactants of the poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (EOx-POy-EOx) range, from which the nature of the polymeric interface could be characterised. The data follow a pronounced Q(-4) decay, along with a number of inflexi...

Polymeric alkylpyridinium salts (poly-APS) isolated from the marine sponge Reniera sarai act as potent anticholinesterase agents; in addition they show moderate hemolytic and cytotoxic activities. The hemolytic activity of poly-APS is due to their detergent-like structure and behavior in aqueous solutions. In this work, the hemolytic activity of poly-APS is analyzed and compared to that of stru...

Propolis is a chemically complex resinous bee product which has gained worldwide popularity as a means to improve health condition and prevent diseases. The main constituents of an aqueous extract of a sample of green propolis from Southeast Brazil were shown by high performance liquid chromatography/mass spectroscopy/mass spectroscopy to be mono- and di-O-caffeoylquinic acids; phenylpropanoids...

Background Marine sponges are a rich source of novel biologically active substances such as haemolytic proteins, hemagglutinins and proteins with antimicrobial, antiviral and antifungal activity. Toxic water-soluble polymeric 3alkylpyridinum salts (poly-APS) have been isolated from the marine sponge Reniera sarai. Poly-APS has pore-forming properties expressed in a dose-dependent manner. These ...

Polymeric alkylpyridinium salts (poly-APS) isolated from the marine sponge Reniera sarai act as antifouling and anticholinesterase agents. They also show moderate haemolytic and cytotoxic activities against different cell lines. The haemolytic activity of poly-APS is due to their detergent-like structure and behaviour in aqueous solutions. In this work, the lytic activity of poly-APS against fr...

Interfacial solar evaporation has attracted substantial research interest as an eco-friendly means of desalination. A great deal work been devoted to exploring broad-spectrum absorbers, porous floating systems, and appropriate thermal insulations. During desalination, salt accumulation may block the channel severely decline rate. Herein, we designed a salt-resistant evaporator ([email protected...