ture of our Indian diseases ; but there is evidence to show from record that it was not absolutely unknown to the practitioners of the Hindu system of medicine. The ancients gave the name Diabetes or Bohumootra (Polyuria) to a group of symptoms, the most prominent being augmented secretion of urine, thirst, dry skin, gradual emaciation and loss of strength. For want of a sufficient knowledge of...

Day and night urine volume, morning and evening body weight, and supine and sitting blood pressure were measured in five patients with chronic autonomic failure who were not receiving treatment with drugs. All had nocturnal polyuria, overnight weight loss, and a pronounced postural fall in blood pressure, with lowest levels in the morning. Desmopressin (2-4 micrograms given intramuscularly at 8...

BACKGROUND Nocturia is a common cause of sleep disturbance affecting up to 40% of the adult population. OBJECTIVE This article provides a framework for the management of nocturia. Based on the frequency volume chart, nocturia can be divided into three categories: global polyuria, nocturnal polyuria and bladder storage disorders. Differentiating between these categories enables effective targe...

A 45-year-old man, with a 10-year history of manic depression treated with lithium, was admitted with hyperosmolar, nonketotic coma. He gave a five-year history of polyuria and polydipsia, during which time urinalysis had been negative for glucose. After recovery from hyperglycaemia, he remained polyuric despite normal blood glucose concentrations; water deprivation testing indicated nephrogeni...

A patient with beta hCG-secreting germ cell carcinoma of the pineal and suprasellar regions presented with hydrocephalus, Parinaud's syndrome, hypopituitarism and polyuria. Central diabetes insipidus was strongly suspected although the water deprivation test was not diagnostic. The polyuria however, responded to ADH analogue when the hypothyroidism and hypocortisolism were treated. Pubertal dev...

Diabetes insipidus is a rare endocrine disorder in paediatric patients. Polyuria is a cardinal manifestation that is extremely difficult to recognize in diapered infants. Careful urine quantification is the key to diagnosis in appropriate clinical setting. We report a case of a 4 months old infant presenting with an acute life threatening event following an episode of vomiting and decreased ora...