نتایج جستجو برای: poor ovarian function

تعداد نتایج: 1494183  

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه شهید چمران اهواز - دانشکده ریاضی 1391

در این پایان نامه مدول هایی را تعریف می کنیم که دامنه انژکتیو آن فقط شامل r-مدول های نیم ساده است و چنین مدولی را poor می نامیم. همچنین نشان می دهیم همه حلقه ها دارای poor-مدول هستند. علاوه بر این حلقه بدون کلاس میانی راست را تعریف کرده و نشان می دهیم یک حلقه بدون کلاس میانی راست، جمعوند مستقیم یک حلقه نیم ساده آرتینی و یک حلقه t است که حلقه t دارای ویژگی های خاصی است که به طور کامل به آن پرداخ...

2014
Cheng-Fei Liu Shu-Yan Liu Xiao-Yun Min Yuan-Yuan Ji Na Wang Dan Liu Ning Ma Zong-Fang Li Ke Li

OBJECTIVE Recent reports have shown that C-X-C chemokine receptor 4 (CXCR4) is expressed in ovarian cancer and plays an important role in metastasis. However, the prognostic value of CXCR4 in ovarian cancer remains controversial and has not been emphasized. The aim of this study is to evaluate the prognostic significance of CXCR4 in ovarian cancer by performing a meta-analysis. METHODS We sys...

Journal: :Reproductive biomedicine online 2014
Nikolaos P Polyzos Milie Nwoye Roberta Corona Christophe Blockeel Dominic Stoop Patrick Haentjens Michel Camus Herman Tournaye

This retrospective study determined the efficacy of ovarian stimulation for IVF/intracytoplasmic sperm injection (ICSI) in poor ovarian responders fulfilling the Bologna criteria for poor ovarian response and identified predictors of live birth rates. Overall, 485 patients undergoing 823 ovarian stimulation cycles for IVF/ICSI with maximum gonadotrophin dose (≥ 300 IU) between January 2009 and ...

Journal: :Reproductive biology and endocrinology : RB&E 2016
Norbert Gleicher Vitaly A Kushnir Andrea Weghofer David H Barad

BACKGROUND Low testosterone (T), whether due to ovarian and/or adrenal insufficiency, usually results in poor follicle maturation at small growing follicle stages. The consequence is a phenotype of low functional ovarian reserve (LFOR), characterized by poor granulosa cell mass, low anti-Müllerian hormone and estradiol but rising follicle stimulating hormone. Such hypoandrogenism can be of ovar...

Journal: :Cancer research 2003
Tiina-Liisa Erkinheimo Heini Lassus Anna Sivula Sibani Sengupta Henry Furneaux Timothy Hla Caj Haglund Ralf Butzow Ari Ristimäki

Cyclooxygenase-2 (COX-2) expression has been shown to associate with poor prognosis in ovarian cancer, and an mRNA stability protein HuR has been shown to enhance expression of COX-2 in tissue culture conditions. We found cytoplasmic immunoreactivity for HuR protein in 52% (233 of 445) of serous-type ovarian carcinoma specimens, and it associated with high COX-2 expression (P = 0.0045) and with...

2013
Mi Jeong Kwon Young Kee Shin

Cancer stem cells or tumor-initiating cells (CSC/TICs), which can undergo self-renewal and differentiation, are thought to play critical roles in tumorigenesis, therapy resistance, tumor recurrence and metastasis. Tumor recurrence and chemoresistance are major causes of poor survival rates of ovarian cancer patients, which may be due in part to the existence of CSC/TICs. Therefore, elucidating ...

2016
Hyun Jong Park Geun Ho Lee Du Sik Gong Tae Ki Yoon Woo Sik Lee

Measurements of ovarian reserve play an important role in predicting the clinical results of assisted reproductive technology (ART). The ideal markers of ovarian reserve for clinical applications should have high specificity in order to determine genuine poor responders. Basal follicle-stimulating hormone levels, antral follicle count, and serum anti-Müllerian hormone (AMH) levels have been sug...

2006
KEIICHIRO NAKAMURA YASUTOMO NASU ATSUSHI HONGO TAMAKI MATSUO JUNICHI KODAMA SHIN EBARA ATSUSHI NAGAI FERNANDO ABRZUA HIROMI KUMON YUJI HIRAMATSU

In light of the poor prognosis for ovarian cancer patients, the research continues for innovative and efficacious treatment modalities. Along with surgical and chemotherapeutic regimens, gene therapy has emerged as one of the leading contenders in the treatment armamentarium. Hepsin is a type II transmembrane serine protease originally identified in the human liver as a cDNA clone. However, the...

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