Crystal structures of protein-ligand complexes are often used to infer biology and inform structure-based drug discovery. Hence, it is important to build accurate, reliable models of ligands that give confidence in the interpretation of the respective protein-ligand complex. This paper discusses key stages in the ligand-fitting process, including ligand binding-site identification, ligand descr...

By the Telescope Conjecture for Module Categories, we mean the following claim: “Let R be any ring and (A,B) be a hereditary cotorsion pair in Mod-R with A and B closed under direct limits. Then (A,B) is of finite type.” We prove a modification of this conjecture with the word ‘finite’ replaced by ‘countable’. We show that a hereditary cotorsion pair (A,B) of modules over an arbitrary ring R is...

© ThriftyTorrent: Cheap P2P software patch distribution for enterprise networks Miranda Mowbray, Chris Peltz, Cristiano Costa, Nazareno Andrade, Katia Saikoski HP Laboratories HPL-2009-80

BACKGROUND Information regarding the health status of migrants compared to subjects who remain in the country of origin is scarce. We compared the levels and management of the main cardiovascular risk factors between Portuguese living in Porto (Portugal) and Portuguese migrants living in Lausanne (Switzerland). METHODS Cross-sectional studies conducted in Porto (EPIPorto, 1999 to 2003, n = 11...

The Per-Fide project is a joint collaboration between researchers at the Department of Informatics and the Institute of Arts and Humanities at the University of Minho, Portugal. The acronym Per-Fide stands for Portuguese (P) in parallel with 6 languages: English (E), Russian (R), French (F), Italian (I), German/Deutsch (D) and Spanish/ Español (E). First, we expound on the role of the Per-Fide ...

Comparative Issues in Romanian Syntax held at the University of New Brunswick, Saint John, Canada; at the 1996 Going Romance conference held in Utrecht, the Netherlands; at the 1997 Linguistic Symposium on Romance Languages held at UC Irvine, and at the 1997 Hopkins Optimality Theory Workshop & University of Maryland Mayfest in Baltimore. I would like to thank audiences at these meetings for th...