background : to determine the role of letrozole, an aromatase inhibitor,in the treatment of endometriotic pain.   methods: in this prospective, randomized, controlled clinical trial in minimallyinvasive surgery research center,51 women with pelvic endometriosis and endometriotic pain (dyspareunia, dysmenorrhea, pelvic pain) score of 5 or more (for at least one of these endometriotic pain), afte...

introduction: chronic radicular low back pain is a common disease that limits patient’s daily activity. epidural steroid injection (esi) is becoming the mainstay of therapies for radicular low back pain due to contained bulged disc. aim: to determine the effect of adding hypertonic saline to epidural steroid injections to provide pain relief for chronic radiculopathy back pain secondary to fora...

OBJECTIVE This study was designed to evaluate the difference in the degree of patient pain for an ultrasound-guided fine-needle aspiration biopsy (USFNAB) of a thyroid nodule with one needle puncture with and without local anesthesia. MATERIALS AND METHODS A total of 50 patients participated in the study. We examined prospective patients who would undergo US-FNABs of two thyroid nodules (larg...

OBJECTIVE To test the hypothesis that psychological treatment given in combination with somatic treatment can relieve recurrent abdominal pain (RAP) of psychosomatic origin in childhood. STUDY DESIGN Stomach Pain Clinic Group A, comprising 25 children receiving a combination of psychological treatment and physiotherapy given by two different persons and Stomach Pain Clinic Group B, comprising...

BACKGROUND There is a belief that the amount of pain perceived is merely directly proportional to the extent of injury. The intensity of postoperative pain is however influenced by multiple factors aside from the extent of trauma. The purpose of the study was to evaluate the relationship between preoperative factors that have been shown to predict postoperative pain and the self-reports of pain...

BACKGROUND Offset analgesia, in which a disproportionally large amount of analgesia becomes apparent upon a slight decrease in noxious heat stimulation, has not been described previously in patients with chronic pain. METHODS Offset analgesia responses in 10 patients with neuropathic pain (in both legs) were compared with 10 matched healthy controls and volunteers from a convenience sample (n...

BACKGROUND Chronic obstructive pulmonary disease (COPD) is a great public health burden worldwide. Few studies have focused on pain problems in patients with mild and moderate COPD in Chinese community settings. METHODS A cross-sectional study of 283 patients with mild and moderate COPD was conducted in six communities that were randomly sampled in Pudong New Area of Shanghai, China, in 2016....

Introduction: The aim of the present study was to evaluate the efficacy and safety profile of bone palliative therapy following administration of 153Sm-EDTMP in patients with intractable metastatic bone pain. Methods: Sixteen patients (9 male, 7 female) aged 29-80 years (57.3±16.7 years) with severe metastasis-related bone pain resistant to analgesic medications were enrolled in the...