introduction: in the present work, spontaneous postsynaptic currents were assessed to investigate the postnatal development of excitatory postsynaptic currents in locus coeruleus neurons. methods: in this study, ampa and nmda receptor-mediated spontaneous synaptic currents in the neurons of locus coeruleus were assessed using whole cell voltage-clamp recording during the first three weeks. resu...

OBJECTIVES The aim of this study was to investigate people's attitude towards providing symptom information electronically before a consultation. Specific areas investigated include a) attitudes and experiences with regards to acquisition of information related to symptoms, b) attitudes towards computer based communication of symptoms to the general practitioner and how they preferred to carry ...

introduction: motor behavior and coordination impairment are known side effects of opioid treatment, yet very few studies have investigated the effects of tramadol on motor behavior, or compared its effect with the effect of an opioid. this study investigates the effects of chronic injection of morphine and tramadol on rat motor function during infancy. methods: neonate rats (n=56) were randoml...

OBJECTIVE To analyze the risk factors associated with neonatal deaths among children with low birth weight. METHODS A cohort study was carried out on live births weighing between 500 g and 2,499 g from single pregnancies without anencephaly in Recife (Northeastern Brazil) between 2001 and 2003. Data on 5,687 live births and 499 neonatal deaths obtained from the Live Birth Information System a...

Objective. The prevalence of antenatal depression (AD) and associated risk factors among pregnant women attending antenatal clinics in Abeokuta North Local Government Area, Nigeria, was determined. Methods. A descriptive cross-sectional survey was conducted, interviewing 314 pregnant women selected by multistage sampling technique from among those attending antenatal clinics. Information was co...

Abstract Postnatal depression (PND) is an important public health problem with far-reaching consequences for mothers, families, and society. Current treatment approaches tend to focus on the depressive symptoms of mother. We propose need a shift in conceptualisation PND its management, by focusing circadian rhythm as early manifestation mother-infant synchrony. have reviewed relevant interdisci...

OBJECTIVE To assess the socioeconomic, geographical and demographic inequities in the use of postnatal health-care services in low- and middle-income countries. METHODS We searched Medline, Embase and Cochrane Central databases and grey literature for experimental, quasi-experimental and observational studies that had been conducted in low- and middle-income countries. We summarized the relev...

objective: elevated amino acid homocysteine (hcy) levels and insufficient physical activity are the risk factors in alzheimer disease (ad) development. the effect of intermittent aerobic training on memory retention test and thiobarbituric acid reactive substances (tbars) and superoxide dismutase (sod) levels in the dorsal hippocampus of rats which were stimulated with hcy is investigated. meth...

BACKGROUND Evidence for the use of telephone consultation in childhood inflammatory bowel disease (IBD) is lacking. We aimed to assess the effectiveness and cost consequences of telephone consultation compared with the usual out-patient face-to-face consultation for young people with IBD. METHODS We conducted a randomised-controlled trial in Manchester, UK, between July 12, 2010 and June 30, ...