Abstract Background/Introduction Oxidative stress plays an important role in the pathogenesis of type 2 diabetes mellitus. Purpose We aimed to investigate oxidative and nitrites/nitrates concentrations at baseline during postprandial hyperglycaemia 40 first-degree relatives (FDR) diabetic patients with normal oral glucose test (OGTT), subjects abnormal OGTT (dysglycaemic) 20 without parental hi...

Acute hyperglycaemia has been associated with complications, prolonged intensive care unit and hospital stay, and increased mortality. We made an inventory of the prevalence and prognostic value of hyperglycaemia, and of the effects of glucose control in different groups of critically ill patients. The prevalence of hyperglycaemia in critically ill patients, using stringent criteria, approaches...

Background: Diabetes mellitus (DM) is a complex metabolic disorder which involves multiple pathology manifested with increased blood glucose, neural degeneration, chronic inflammation, organ dysfunction etc. Hyperactive enzymes like alpha amylase and glucosidase that are involved in digestion of starch sucrose further upswings the postprandial hyperglycaemia by rushing excess glucose moieties i...

OBJECTIVE Our primary objective was to determine the impact of prior exposure to hyperglycaemia on the association between glycaemic variability during critical illness and mortality. Our secondary objectives included evaluating the relationships between prior hyperglycaemia and hyperglycaemia or hypoglycaemia during critical illness and mortality. DESIGN AND PARTICIPANTS A single-centre, ret...

Introduction. Since 1999 continuous glucose monitoring (CGM) has been used to measure the amount of in interstitial fluid. CGM is crucial when it comes developing ambulatory profile and giving information on time spent range (TIR), percentage above below range, as well variability. Discussion. It was 1992 that Campbell et al. first described white coat hyperglycaemia, who explained patients hav...

Background. HIV patients on highly active antiretroviral therapy (HAART) containing protease inhibitors (PIs) had been often associated with lipodystrophy. However, there are only few studies on association of nucleoside and nonnucleoside reverse transcriptase inhibitors (NRTI and NNRTI) with lipodystrophy. Study Design. One hundred and one HIV male patients were categorised into ART naïve (n =...